WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 526349
Description: YU142670 is a novel selective inhibitor against OCRL1/INPP5F and OCRL2/INPP5B by targeting OCRL catalytic domain.
MedKoo Cat#: 526349
Chemical Formula: C8H5N5S
Exact Mass: 203.0266
Molecular Weight: 203.223
Elemental Analysis: C, 47.28; H, 2.48; N, 34.46; S, 15.78
Synonym: YU142670, YU 142670, YU-142670
IUPAC/Chemical Name: 3-(4-Pyridinyl)-1,2,4-triazolo[3,4-b][1,3,4]thiadiazole
InChi Key: HRBYAJQMVADJHW-UHFFFAOYSA-N
InChi Code: InChI=1S/C8H5N5S/c1-3-9-4-2-6(1)7-11-12-8-13(7)10-5-14-8/h1-5H
SMILES Code: C12=NN=C(C3=CC=NC=C3)N1N=CS2
Appearance: White to light brown solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 203.223 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Pirruccello M, Nandez R, Idevall-Hagren O, Alcazar-Roman A, Abriola L, Berwick SA, Lucast L, Morel D, De Camilli P. Identification of inhibitors of inositol 5-phosphatases through multiple screening strategies. ACS Chem Biol. 2014 Jun 20;9(6):1359-68. doi: 10.1021/cb500161z. Epub 2014 May 1. PubMed PMID: 24742366; PubMed Central PMCID: PMC4076014.