Saccharin 1-methylimidazole

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 526295

CAS#: 482333-74-4

Description: Saccharin 1-methylimidazole, also known as SMI, is an activator for DNA and RNA synthesis.

Chemical Structure

Saccharin 1-methylimidazole
CAS# 482333-74-4

Theoretical Analysis

MedKoo Cat#: 526295
Name: Saccharin 1-methylimidazole
CAS#: 482333-74-4
Chemical Formula: C11H11N3O3S
Exact Mass: 265.0521
Molecular Weight: 265.287
Elemental Analysis: C, 49.80; H, 4.18; N, 15.84; O, 18.09; S, 12.09

Price and Availability

Size Price Availability Quantity
100.0mg USD 250.0 Ready to ship
200.0mg USD 450.0 Ready to ship
500.0mg USD 950.0 Ready to ship
1.0g USD 1450.0 Ready to ship
2.0g USD 2450.0 Ready to ship
5.0g USD 4950.0 Ready to ship
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Synonym: Saccharin 1-methylimidazole; SMI;

IUPAC/Chemical Name: 1,1-Dioxide-1,2-benzisothiazol-3(2H)-one 1-methyl-1H-imidazole salt


InChi Code: InChI=1S/C7H5NO3S.C4H6N2/c9-7-5-3-1-2-4-6(5)12(10,11)8-7;1-6-3-2-5-4-6/h1-4H,(H,8,9);2-4H,1H3

SMILES Code: O=S(C1=C(C=CC=C1)C2=O)(N2)=O.CN3C=NC=C3

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
DMSO 52.67 198.54
Water 53.0 199.78
Ethanol 31.5 118.74
DMF 5.0 18.85
PBS (pH 7.2) 10.0 37.69

Preparing Stock Solutions

The following data is based on the product molecular weight 265.287 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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