Cuelure
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 540093

CAS#: 3572-06-3

Description: Cuelure is a hormonal attractant for male Bactrocera flies.

Chemical Structure

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Cuelure
CAS# 3572-06-3
Instruction

Theoretical Analysis

MedKoo Cat#: 540093
Name: Cuelure
CAS#: 3572-06-3
Chemical Formula: C12H14O3
Exact Mass: 206.09
Molecular Weight: 206.240
Elemental Analysis: C, 69.89; H, 6.84; O, 23.27

Price and Availability

Size Price Availability Quantity
100mg USD 190
250mg USD 350
500mg USD 650
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Synonym: 4-(p-Acetoxyphenyl)-2-butanone; AI3-31833; AI331833; AI3 31833; BRN-1961620; BRN1961620; BRN 1961620;

IUPAC/Chemical Name: 4-(3-oxobutyl)phenyl acetate

InChi Key: UMIKWXDGXDJQJK-UHFFFAOYSA-N

InChi Code: InChI=1S/C12H14O3/c1-9(13)3-4-11-5-7-12(8-6-11)15-10(2)14/h5-8H,3-4H2,1-2H3

SMILES Code: CC(CCC1=CC=C(OC(C)=O)C=C1)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 206.24 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Kumaran N, Hayes RA, Clarke AR. Cuelure but not zingerone make the sex pheromone of male Bactrocera tryoni (Tephritidae: Diptera) more attractive to females. J Insect Physiol. 2014 Sep;68:36-43. doi: 10.1016/j.jinsphys.2014.06.015. Epub 2014 Jul 7. PubMed PMID: 25010549.

2: Dominiak BC, Campbell AJ, Jang EB, Ramsey A, Fanson BG. Field Evaluation of Melolure, a Formate Analogue of Cuelure, and Reassessment of Fruit Fly Species Trapped in Sydney, New South Wales, Australia. J Econ Entomol. 2015 Jun;108(3):1176-81. doi: 10.1093/jee/tov048. Epub 2015 Mar 30. PubMed PMID: 26470243.

3: Siderhurst MS, Park SJ, Buller CN, Jamie IM, Manoukis NC, Jang EB, Taylor PW. Raspberry Ketone Trifluoroacetate, a New Attractant for the Queensland Fruit Fly, Bactrocera Tryoni (Froggatt). J Chem Ecol. 2016 Feb;42(2):156-62. doi: 10.1007/s10886-016-0673-3. Epub 2016 Feb 27. PubMed PMID: 26922349.

4: Kumaran N, Prentis PJ, Mangalam KP, Schutze MK, Clarke AR. Sexual selection in true fruit flies (Diptera: Tephritidae): transcriptome and experimental evidences for phytochemicals increasing male competitive ability. Mol Ecol. 2014 Sep;23(18):4645-57. doi: 10.1111/mec.12880. Epub 2014 Sep 6. PubMed PMID: 25112896.

5: Jang EB, Casana-Giner V, Oliver JE. Field captures of wild melon fly (Diptera: Tephritidae) with an improved male attractant, raspberry ketone formate. J Econ Entomol. 2007 Aug;100(4):1124-8. PubMed PMID: 17849860.

6: Suckling DM, Jang EB, Carvalho LA, Nagata JT, Schneider EL, El-Sayed AM. Can ménage-a-trois be used for controlling insects? J Chem Ecol. 2007 Aug;33(8):1494-504. Epub 2007 Jul 6. PubMed PMID: 17619106.

7: Dominiak BC, Nicol HI. Field performance of Lynfield and McPhail traps for monitoring male and female sterile Bactrocera tryoni (Froggatt) and wild Dacus newmani (Perkins). Pest Manag Sci. 2010 Jul;66(7):741-4. doi: 10.1002/ps.1936. PubMed PMID: 20309994.

8: Chang CL, Cho IK, Li QX. Insecticidal activity of basil oil, trans-anethole, estragole, and linalool to adult fruit flies of Ceratitis capitata, Bactrocera dorsalis, and Bactrocera cucurbitae. J Econ Entomol. 2009 Feb;102(1):203-9. PubMed PMID: 19253638.

9: Reynolds OL, Osborne T, Crisp P, Barchia IM. Specialized Pheromone and Lure Application Technology as an Alternative Male Annihilation Technique to Manage Bactrocera tryoni (Diptera: Tephritidae). J Econ Entomol. 2016 Mar 27. pii: tow023. [Epub ahead of print] PubMed PMID: 27018434.

10: Vargas RI, Shelly TE, Leblanc L, Piñero JC. Recent advances in methyl eugenol and cue-lure technologies for fruit fly detection, monitoring, and control in Hawaii. Vitam Horm. 2010;83:575-95. doi: 10.1016/S0083-6729(10)83023-7. Review. PubMed PMID: 20831962.

11: Vargas RI, Burns RE, Mau RF, Stark JD, Cook P, Piñero JC. Captures in methyl eugenol and cue-lure detection traps with and without insecticides and with a Farma Tech solid lure and insecticide dispenser. J Econ Entomol. 2009 Apr;102(2):552-7. PubMed PMID: 19449634.

12: Suckling DM, Jang EB, Holder P, Carvalho L, Stephens AE. Evaluation of lure dispensers for fruit fly surveillance in New Zealand. Pest Manag Sci. 2008 Aug;64(8):848-56. doi: 10.1002/ps.1578. PubMed PMID: 18383565.

13: Leblanc L, Rubinoff D, Vargas RI. Attraction of nontarget species to fruit fly (Diptera: tephritidae) male lures and decaying fruit flies in traps in hawaii. Environ Entomol. 2009 Oct;38(5):1446-61. PubMed PMID: 19825300.

14: Vargas RI, Mau RF, Stark JD, Piñero JC, Leblanc L, Souder SK. Evaluation of methyl eugenol and cue-lure traps with solid lure and insecticide dispensers for fruit fly monitoring and male annihilation in the Hawaii Areawide Pest Management Program. J Econ Entomol. 2010 Apr;103(2):409-15. PubMed PMID: 20429456.

15: Vargas RI, Miller NW, Stark JD. Field trials of spinosad as a replacement for naled, DDVP, and malathion in methyl eugenol and cue-lure bucket traps to attract and kill male oriental fruit flies and melon flies (Diptera: Tephritidae) in Hawaii. J Econ Entomol. 2003 Dec;96(6):1780-5. PubMed PMID: 14977115.

16: Vargas RI, Stark JD, Hertlein M, Neto AM, Coler R, Piñero JC. Evaluation of SPLAT with spinosad and methyl eugenol or cue-lure for "attract-and-kill" of oriental and melon fruit flies (Diptera: Tephritidae) in Hawaii. J Econ Entomol. 2008 Jun;101(3):759-68. PubMed PMID: 18613576.

17: Smith PT, Kambhampati S, Armstrong KA. Phylogenetic relationships among Bactrocera species (Diptera: Tephritidae) inferred from mitochondrial DNA sequences. Mol Phylogenet Evol. 2003 Jan;26(1):8-17. PubMed PMID: 12470933.

18: Wong TT, McInnis DO, Ramadan MM, Nishimoto JI. Age-related response of male melon fliesDacus cucurbitae (Diptera: Tephritidae) to cue-lure. J Chem Ecol. 1991 Dec;17(12):2481-7. doi: 10.1007/BF00994596. PubMed PMID: 24258641.

19: Doolittle RE, Beroza M, Keiser I, Schneider EL. Deuteration of the melon fly attractant, cue-lure, and its effect on olfactory response and infra-red absorption. J Insect Physiol. 1968 Dec;14(12):1697-712. PubMed PMID: 5733972.

20: Holbrook FR, Steiner LF, Fujimoto MS, Cunningham RT. Effects of location on responses of male melon flies to fiberboard blocks impregnated with cue-lure, a male attractant. J Econ Entomol. 1970 Jun;63(3):869-70. PubMed PMID: 5431681.