Sulfaclozine | CAS#102-65-8

Sulfaclozine
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WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 526009

CAS#: 102-65-8 (free)

Description: Sulfaclozine is an antiprotozoal.

Chemical Structure

Sulfaclozine

CAS# 102-65-8 (free)

Instruction

Theoretical Analysis

MedKoo Cat#: 526009
Name: Sulfaclozine
CAS#: 102-65-8 (free)
Chemical Formula: C10H9ClN4O2S
Exact Mass: 284.01
Molecular Weight: 284.718
Elemental Analysis: C, 42.19; H, 3.19; Cl, 12.45; N, 19.68; O, 11.24; S, 11.26

Price and Availability

Size	Price	Availability	Quantity
100mg	USD 250	2 Weeks
Bulk inquiry Welcome, Customer: Please do not inquire quote if your intended use is for a patient since our products are for research use and for chemical synthesis use, not for human use . For in-stock products, we listed price in the web page. You may inquire prices for which sizes were not listed. If no price is listed, this means the product is not in stock at the moment, which may be available via custom synthesis. For cost-effective reason, minimum order of 1g is requested (typically very expensive). The lead time is usually 2-4 months. Quote of less than 1g will not be provided. MedKoo may not offer quote for below reasons: (1) current available synthetic method appears to be extremely expensive which is obviously not affordable to most customers; (2) Key raw material to make the product is temporally not available; (3) DEA controlled substances; (4) the product is under patent protection in customer’s country.

Related CAS #: 102-65-8 (free); 23307-72-4 (sodium);

Synonym: Sulfaclozine

IUPAC/Chemical Name: 4-Amino-N-(6-chloropyrazin-2-yl)benzenesulfonamide

InChi Key: QKLPUVXBJHRFQZ-UHFFFAOYSA-N

InChi Code: InChI=1S/C10H9ClN4O2S/c11-9-5-13-6-10(14-9)15-18(16,17)8-3-1-7(12)2-4-8/h1-6H,12H2,(H,14,15)

SMILES Code: O=S(C1=CC=C(N)C=C1)(NC2=NC(Cl)=CN=C2)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Instruction:

View handling instruction

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 284.72 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Gorissen B, Reyns T, Devreese M, De Backer P, Van Loco J, Croubels S. Determination of selected veterinary antimicrobials in poultry excreta by UHPLC-MS/MS, for application in Salmonella control programs. Anal Bioanal Chem. 2015 Jun;407(15):4447-57. doi: 10.1007/s00216-014-8449-5. Epub 2015 Jan 30. PubMed PMID: 25633214.

2: Yamaguchi T, Okihashi M, Harada K, Konishi Y, Uchida K, Do MH, Bui HD, Nguyen TD, Nguyen PD, Chau VV, Dao KT, Nguyen HT, Kajimura K, Kumeda Y, Bui CT, Vien MQ, Le NH, Hirata K, Yamamoto Y. Antibiotic residue monitoring results for pork, chicken, and beef samples in Vietnam in 2012-2013. J Agric Food Chem. 2015 Jun 3;63(21):5141-5. doi: 10.1021/jf505254y. Epub 2015 Jan 28. PubMed PMID: 25601049.

3: Hu F, Bian K, Liu Y, Su Y, Zhou T, Song X, He L. Development of a modified QUick, Easy, CHeap, Effective, Rugged and Safe method for the determination of multi-class antimicrobials in vegetables by liquid chromatography tandem mass spectrometry. J Chromatogr A. 2014 Nov 14;1368:52-63. doi: 10.1016/j.chroma.2014.09.074. Epub 2014 Oct 5. PubMed PMID: 25311488.

4: Dalla Bona M, Di Leva V, De Liguoro M. The sensitivity of Daphnia magna and Daphnia curvirostris to 10 veterinary antibacterials and to some of their binary mixtures. Chemosphere. 2014 Nov;115:67-74. doi: 10.1016/j.chemosphere.2014.02.003. Epub 2014 Mar 12. PubMed PMID: 24630458.

5: Sheridan R, Mirabile J, Hafler K. Determination of six illegal antibiotics in chicken jerky dog treats. J Agric Food Chem. 2014 Apr 30;62(17):3690-6. doi: 10.1021/jf405458m. Epub 2014 Jan 29. PubMed PMID: 24437928.

6: Yu H, Tao Y, Chen D, Wang Y, Huang L, Peng D, Dai M, Liu Z, Wang X, Yuan Z. Development of a high performance liquid chromatography method and a liquid chromatography-tandem mass spectrometry method with the pressurized liquid extraction for the quantification and confirmation of sulfonamides in the foods of animal origin. J Chromatogr B Analyt Technol Biomed Life Sci. 2011 Sep 1;879(25):2653-62. doi: 10.1016/j.jchromb.2011.07.032. Epub 2011 Jul 30. PubMed PMID: 21840270.

7: Harfoush MA, Hegazy AM, Soliman AH, Amer S. Drug resistance evaluation of some commonly used anti-coccidial drugs in broiler chickens. J Egypt Soc Parasitol. 2010 Aug;40(2):337-48. PubMed PMID: 21246941.

8: Sentepe I, Eraslan G. Pharmacokinetic of sulfaclozine in broiler chickens. Food Chem Toxicol. 2010 Jan;48(1):448-51. doi: 10.1016/j.fct.2009.10.044. Epub 2009 Nov 1. PubMed PMID: 19887098.

9: Braunius WW. [Monensin/sulfachlorpyrazine poisoning in turkeys]. Tijdschr Diergeneeskd. 1986 Jul 15;111(14):676-8. Dutch. PubMed PMID: 3750301.

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