ZM 253270

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 533006

CAS#: 169340-04-9

Description: ZM 253270 is a new class of nonpeptide neurokinin A antagonist.

Price and Availability




ZM 253270 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 533006
Name: ZM 253270
CAS#: 169340-04-9
Chemical Formula: C22H26ClN7O3
Exact Mass: 471.1786
Molecular Weight: 471.95
Elemental Analysis: C, 55.99; H, 5.55; Cl, 7.51; N, 20.78; O, 10.17

Synonym: ZM 253270; ZM253270; ZM-253270.

IUPAC/Chemical Name: 4-[(4-chlorophenyl)amino]-2-[4-[(2E)-2-hydroxyiminopropanoyl]piperazin-1-yl]-6-propan-2-yl-5H-pyrrolo[4,3-e]pyrimidin-7-one


InChi Code: InChI=1S/C22H26ClN7O3/c1-13(2)30-12-17-18(21(30)32)25-22(26-19(17)24-16-6-4-15(23)5-7-16)29-10-8-28(9-11-29)20(31)14(3)27-33/h4-7,13,33H,8-12H2,1-3H3,(H,24,25,26)/b27-14+

SMILES Code: O=C1N(C(C)C)CC2=C(NC3=CC=C(Cl)C=C3)N=C(N4CCN(C(/C(C)=N/O)=O)CC4)N=C21

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:


1: Aharony D, Buckner CK, Ellis JL, Ghanekar SV, Graham A, Kays JS, Little J, Meeker S, Miller SC, Undem BJ, et al. Pharmacological characterization of a new class of nonpeptide neurokinin A antagonists that demonstrate species selectivity. J Pharmacol Exp Ther. 1995 Sep;274(3):1216-21. PubMed PMID: 7562491.