WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 525862
CAS#: 1964457-41-7
Description: YPC-22026 is a novel inducer of tumor regression accompanied by the suppression of ZNF143-regulated genes in a mouse xenograft model.
MedKoo Cat#: 525862
Name: YPC-22026
CAS#: 1964457-41-7
Chemical Formula: C16H8F3N3O2
Exact Mass: 331.0569
Molecular Weight: 331.2542
Elemental Analysis: C, 58.01; H, 2.43; F, 17.21; N, 12.69; O, 9.66
This product is not in stock, which may be available by custom synthesis.
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Synonym: YPC-22026, YPC 22026, YPC22026
IUPAC/Chemical Name: 2-(Pyridine-3-ylethynyl)-5-(2-(trifluoromethoxy)phenyl)-1,3,4-oxadiazole
InChi Key: VLFRKDUUDBAGQX-UHFFFAOYSA-N
InChi Code: InChI=1S/C16H8F3N3O2/c17-16(18,19)24-13-6-2-1-5-12(13)15-22-21-14(23-15)8-7-11-4-3-9-20-10-11/h1-6,9-10H
SMILES Code: FC(F)(F)OC1=CC=CC=C1C2=NN=C(C#CC3=CC=CN=C3)O2
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 331.2542 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Haibara H, Yamazaki R, Nishiyama Y, Ono M, Kobayashi T, Hokkyo-Itagaki A, Nishisaka F, Nishiyama H, Kurita A, Matsuzaki T, Izumi H, Kohno K. YPC-21661 and YPC-22026, novel small molecules, inhibit ZNF143 activity in vitro and in vivo. Cancer Sci. 2017 Feb 13. doi: 10.1111/cas.13199. [Epub ahead of print] PubMed PMID: 28192620.
