WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 532902

CAS#: 1220513-59-6

Description: VU0359516 is a positive allosteric modulators of mGluR4.

Chemical Structure

CAS# 1220513-59-6

Theoretical Analysis

MedKoo Cat#: 532902
Name: VU0359516
CAS#: 1220513-59-6
Chemical Formula: C16H13N3O3
Exact Mass: 295.0957
Molecular Weight: 295.3
Elemental Analysis: C, 65.08; H, 4.44; N, 14.23; O, 16.25

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: VU0359516, VU 0359516, VU-0359516

IUPAC/Chemical Name: (6E)-6-(hydroxyimino)-N-(pyridin-2-yl)-2-oxatricyclo[^{3,5}]undeca-1(11),7,9-triene-3-carboxamide


InChi Code: InChI=1S/C16H13N3O3/c20-15(18-13-7-3-4-8-17-13)16-9-11(16)14(19-21)10-5-1-2-6-12(10)22-16/h1-8,11,21H,9H2,(H,17,18,20)/b19-14-


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 295.3 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Williams R, Zhou Y, Niswender CM, Luo Q, Conn PJ, Lindsley CW, Hopkins CR. Re-exploration of the PHCCC Scaffold: Discovery of Improved Positive Allosteric Modulators of mGluR4. ACS Chem Neurosci. 2010 Jun 16;1(6):411-419. PubMed PMID: 20582156; PubMed Central PMCID: PMC2889702.