VU0240382

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 532898

CAS#: 1092550-36-1

Description: VU0240382 is an allosteric agonist activity of selective positive allosteric modulators of metabotropic glutamate receptor subtype 5.


Chemical Structure

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VU0240382
CAS# 1092550-36-1

Theoretical Analysis

MedKoo Cat#: 532898
Name: VU0240382
CAS#: 1092550-36-1
Chemical Formula: C17H13NO
Exact Mass: 247.0997
Molecular Weight: 247.3
Elemental Analysis: C, 82.57; H, 5.30; N, 5.66; O, 6.47

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: VU0240382, VU-0240382, VU 0240382

IUPAC/Chemical Name: 6-(2-phenylethynyl)-1,2,3,4-tetrahydroisoquinolin-1-one

InChi Key: BOVJHNHRQNCDEQ-UHFFFAOYSA-N

InChi Code: InChI=1S/C17H13NO/c19-17-16-9-8-14(12-15(16)10-11-18-17)7-6-13-4-2-1-3-5-13/h1-5,8-9,12H,10-11H2,(H,18,19)

SMILES Code: O=C1NCCC2=C1C=CC(C#CC3=CC=CC=C3)=C2

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 247.3 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Noetzel MJ, Rook JM, Vinson PN, Cho HP, Days E, Zhou Y, Rodriguez AL, Lavreysen H, Stauffer SR, Niswender CM, Xiang Z, Daniels JS, Jones CK, Lindsley CW, Weaver CD, Conn PJ. Functional impact of allosteric agonist activity of selective positive allosteric modulators of metabotropic glutamate receptor subtype 5 in regulating central nervous system function. Mol Pharmacol. 2012 Feb;81(2):120-33. doi: 10.1124/mol.111.075184. Epub 2011 Oct 21. PubMed PMID: 22021324; PubMed Central PMCID: PMC3263948.