UK-356618
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MedKoo CAT#: 532871

CAS#: 230961-08-7

Description: UK-356618 is a matrix metalloproteinase-3 (MMP-3) inhibitor.


Price and Availability

Size Price Shipping out time Quantity
5mg USD 240 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2020-10-29. Prices are subject to change without notice.

UK-356618, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received. Delivery time: overnight (USA/Canada); 3-5 days (worldwide).


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 532871
Name: UK-356618
CAS#: 230961-08-7
Chemical Formula: C34H43N3O4
Exact Mass: 557.3254
Molecular Weight: 557.74
Elemental Analysis: C, 73.22; H, 7.77; N, 7.53; O, 11.47


Synonym: UK-356618, UK356618, UK356618

IUPAC/Chemical Name: (2R)-N-[(2S)-3,3-dimethyl-1-oxo-1-[[(1R)-1-phenylethyl]amino]butan-2-yl]-N'-hydroxy-2-[3-(3-methyl-4-phenylphenyl)propyl]butanediamide

InChi Key: JJHRUUKMPWUYIB-HVOSOHGQSA-N

InChi Code: InChI=1S/C34H43N3O4/c1-23-21-25(19-20-29(23)27-16-10-7-11-17-27)13-12-18-28(22-30(38)37-41)32(39)36-31(34(3,4)5)33(40)35-24(2)26-14-8-6-9-15-26/h6-11,14-17,19-21,24,28,31,41H,12-13,18,22H2,1-5H3,(H,35,40)(H,36,39)(H,37,38)/t24-,28-,31-/m1/s1

SMILES Code: O=C(N[C@@H](C(C)(C)C)C(N[C@@H](C1=CC=CC=C1)C)=O)[C@H](CCCC2=CC=C(C3=CC=CC=C3)C(C)=C2)CC(NO)=O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001


References

1: Hafez S, Abdelsaid M, El-Shafey S, Johnson MH, Fagan SC, Ergul A. Matrix Metalloprotease 3 Exacerbates Hemorrhagic Transformation and Worsens Functional Outcomes in Hyperglycemic Stroke. Stroke. 2016 Mar;47(3):843-51. doi: 10.1161/STROKEAHA.115.011258. Epub 2016 Feb 2. PubMed PMID: 26839355; PubMed Central PMCID: PMC4766051.