UCL-1848 trifluoroacetate salt

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MedKoo CAT#: 532860

CAS#: 201147-53-7

Description: UCL-1848 trifluoroacetate salt is a selective Ca2+-activated, SK potassium channel blocker.

Price and Availability

Size Price Shipping out time Quantity
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Pricing updated 2020-10-30. Prices are subject to change without notice.

UCL1684 is not in stock, but may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 532860
Name: UCL-1848 trifluoroacetate salt
CAS#: 201147-53-7
Chemical Formula: C28H34N42+
Exact Mass: 426.2772
Molecular Weight: 426.61
Elemental Analysis: C, 78.83; H, 8.03; N, 13.13

Synonym: UCL1848, UCL-1848, UCL 1848, UCL-1848 trifluoroacetate salt

IUPAC/Chemical Name: 8,14-Diaza-1,7(1,4)-diquinolinacyclotetradecaphane trifluoroacetate salt


InChi Code: InChI=1S/C28H32N4/c1-7-17-29-25-15-21-31(27-13-5-3-11-23(25)27)19-9-2-10-20-32-22-16-26(30-18-8-1)24-12-4-6-14-28(24)32/h3-6,11-16,21-22H,1-2,7-10,17-20H2/p+2/b29-25+,30-26+

SMILES Code: c1(NCCCCCNc2c(cccc3)c3[n+]4cc2)c5ccccc5[n+](CCCCC4)cc1

Technical Data

White to off-white solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Abdullaev IF, Rudkouskaya A, Mongin AA, Kuo YH. Calcium-activated potassium channels BK and IK1 are functionally expressed in human gliomas but do not regulate cell proliferation. PLoS One. 2010 Aug 20;5(8):e12304. doi: 10.1371/journal.pone.0012304. PubMed PMID: 20808839; PubMed Central PMCID: PMC2924897.

2: Lopez de Armentia M, Sah P. Firing properties and connectivity of neurons in the rat lateral central nucleus of the amygdala. J Neurophysiol. 2004 Sep;92(3):1285-94. Epub 2004 May 5. PubMed PMID: 15128752.

3: Faber ES, Sah P. Physiological role of calcium-activated potassium currents in the rat lateral amygdala. J Neurosci. 2002 Mar 1;22(5):1618-28. PubMed PMID: 11880492.

4: Shah M, Haylett DG. The pharmacology of hSK1 Ca2+-activated K+ channels expressed in mammalian cell lines. Br J Pharmacol. 2000 Feb;129(4):627-30. PubMed PMID: 10683185; PubMed Central PMCID: PMC1571896.