We are open as normal during COVID-19 pandemic. Order online, same day shipping out from North Carolina, USA

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 532849

CAS#: 82657-23-6

Description: NOTE: U-47700 has been discontinued | U-47700 is a selective µ-opioid receptor agonist (Kd = 5.3 and 910 nM for µ- and κ-opioid receptors, respectively, in guinea pig brain) that is 7.5-fold more potent than morphine. U-47700 is an analytical reference material that is structurally categorized as an opioid.

Price and Availability

Size Price Shipping out time Quantity
Inquire bulk and customized quantity

Pricing updated 2020-09-23. Prices are subject to change without notice.

U-47700 is discontinued (DEA controlled substance)

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 532849
Name: U-47700
CAS#: 82657-23-6
Chemical Formula: C16H22Cl2N2O
Exact Mass: 328.1109
Molecular Weight: 329.27
Elemental Analysis: C, 58.37; H, 6.74; Cl, 21.53; N, 8.51; O, 4.86

Synonym: U-47700, U 47700, U47700

IUPAC/Chemical Name: 3,4-dichloro-N-[(1R,2R)-2-(dimethylamino)cyclohexyl]-N-methylbenzamide


InChi Code: InChI=1S/C16H22Cl2N2O/c1-19(2)14-6-4-5-7-15(14)20(3)16(21)11-8-9-12(17)13(18)10-11/h8-10,14-15H,4-7H2,1-3H3/t14-,15-/m1/s1

SMILES Code: O=C(N([C@H]1[C@H](N(C)C)CCCC1)C)C2=CC=C(Cl)C(Cl)=C2

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Dziadosz M, Klintschar M, Teske J. Postmortem concentration distribution in fatal cases involving the synthetic opioid U-47700. Int J Legal Med. 2017 Apr 11. doi: 10.1007/s00414-017-1593-7. [Epub ahead of print] PubMed PMID: 28401304.

2: Metushi I, Schneir A, Fitzgerald R. Identification of Novel Synthetic Opioid U-47700 through a Broad Screen Time of Flight High-Resolution Mass Spectrometry Method. Am J Clin Pathol. 2017 Mar 1;147(suppl_2):S168. doi: 10.1093/ajcp/aqw191.035. PubMed PMID: 28339954.

3: Fleming SW, Cooley JC, Johnson L, Frazee CC, Domanski K, Kleinschmidt K, Garg U. Analysis of U-47700, a Novel Synthetic Opioid, in Human Urine by LC-MS-MS and LC-QToF. J Anal Toxicol. 2017 Apr 1;41(3):173-180. doi: 10.1093/jat/bkw131. PubMed PMID: 28035035.

4: Drug Enforcement Administration, Department of Justice.. Schedules of Controlled Substances: Temporary Placement of U-47700 Into Schedule I. Final order. Fed Regist. 2016 Nov 14;81(219):79389-93. PubMed PMID: 27905978.

5: McIntyre IM, Gary RD, Joseph S, Stabley R. A Fatality Related to the Synthetic Opioid U-47700: Postmortem Concentration Distribution. J Anal Toxicol. 2017 Mar 1;41(2):158-160. doi: 10.1093/jat/bkw124. PubMed PMID: 27798077.

6: Schneir A, Metushi IG, Fitzgerald RL. U-47700 Reply. Clin Toxicol (Phila). 2017 Jan;55(1):73. doi: 10.1080/15563650.2016.1239108. Epub 2016 Oct 17. PubMed PMID: 27744720.

7: Vo KT, van Wijk XM, Wu AH, Lynch KL, Ho RY. Synthetic agents off the darknet: a case of U-47700 and phenazepam abuse. Clin Toxicol (Phila). 2017 Jan;55(1):71-72. doi: 10.1080/15563650.2016.1240806. Epub 2016 Oct 13. PubMed PMID: 27736261.

8: Mohr AL, Friscia M, Papsun D, Kacinko SL, Buzby D, Logan BK. Analysis of Novel Synthetic Opioids U-47700, U-50488 and Furanyl Fentanyl by LC-MS/MS in Postmortem Casework. J Anal Toxicol. 2016 Nov;40(9):709-717. Epub 2016 Sep 1. PubMed PMID: 27590036.

9: Jones MJ, Hernandez BS, Janis GC, Stellpflug SJ. A case of U-47700 overdose with laboratory confirmation and metabolite identification. Clin Toxicol (Phila). 2017 Jan;55(1):55-59. doi: 10.1080/15563650.2016.1209767. Epub 2016 Aug 23. Erratum in: Clin Toxicol (Phila). 2017 Jan;55(1):76. PubMed PMID: 27549165.

10: Armenian P, Olson A, Anaya A, Kurtz A, Ruegner R, Gerona RR. Fentanyl and a Novel Synthetic Opioid U-47700 Masquerading as Street "Norco" in Central California: A Case Report. Ann Emerg Med. 2017 Jan;69(1):87-90. doi: 10.1016/j.annemergmed.2016.06.014. Epub 2016 Jul 26. PubMed PMID: 27473610.

11: Schneir A, Metushi IG, Sloane C, Benaron DJ, Fitzgerald RL. Near death from a novel synthetic opioid labeled U-47700: emergence of a new opioid class. Clin Toxicol (Phila). 2017 Jan;55(1):51-54. doi: 10.1080/15563650.2016.1209764. Epub 2016 Jul 22. PubMed PMID: 27448790.

12: Domanski K, Kleinschmidt KC, Schulte JM, Fleming S, Frazee C, Menendez A, Tavakoli K. Two cases of intoxication with new synthetic opioid, U-47700. Clin Toxicol (Phila). 2017 Jan;55(1):46-50. doi: 10.1080/15563650.2016.1209763. Epub 2016 Jul 19. PubMed PMID: 27432224.

13: Ruan X, Chiravuri S, Kaye AD. Comparing fatal cases involving U-47700. Forensic Sci Med Pathol. 2016 Sep;12(3):369-71. doi: 10.1007/s12024-016-9795-8. Epub 2016 Jul 16. PubMed PMID: 27421264.

14: Coopman V, Blanckaert P, Van Parys G, Van Calenbergh S, Cordonnier J. A case of acute intoxication due to combined use of fentanyl and 3,4-dichloro-N-[2-(dimethylamino)cyclohexyl]-N-methylbenzamide (U-47700). Forensic Sci Int. 2016 Sep;266:68-72. doi: 10.1016/j.forsciint.2016.05.001. Epub 2016 May 13. PubMed PMID: 27235591.

15: Elliott SP, Brandt SD, Smith C. The first reported fatality associated with the synthetic opioid 3,4-dichloro-N-[2-(dimethylamino)cyclohexyl]-N-methylbenzamide (U-47700) and implications for forensic analysis. Drug Test Anal. 2016 Aug;8(8):875-9. doi: 10.1002/dta.1984. Epub 2016 May 27. PubMed PMID: 27232154.