WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 525385

CAS#: 864864-17-5

Description: CFMTI is a potent and selective metabotropic glutamate receptor (mGluR) 1 allosteric antagonist

Price and Availability

Size Price Shipping out time Quantity
100mg USD 1350 2 Weeks
200mg USD 1950 2 Weeks
500mg USD 2650 2 Weeks
1g USD 3450 2 Weeks
2g USD 5250 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2021-01-27. Prices are subject to change without notice.

CFMTI, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 525385
CAS#: 864864-17-5
Chemical Formula: C19H16FN5O
Exact Mass: 349.1339
Molecular Weight: 349.3694
Elemental Analysis: C, 65.32; H, 4.62; F, 5.44; N, 20.05; O, 4.58

Synonym: CFMTI

IUPAC/Chemical Name: 2-Cyclopropyl-5-[1-(2-fluoro-3-pyridinyl)-5-methyl-1H-1,2,3-triazol-4-yl]-2,3-dihydro-1H-isoindol-1-one


InChi Code: InChI=1S/C19H16FN5O/c1-11-17(22-23-25(11)16-3-2-8-21-18(16)20)12-4-7-15-13(9-12)10-24(19(15)26)14-5-6-14/h2-4,7-9,14H,5-6,10H2,1H3

SMILES Code: O=C1N(C2CC2)CC3=C1C=CC(C4=C(C)N(C5=CC=CN=C5F)N=N4)=C3

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Suzuki G, Satow A, Ohta H. Effect of CFMTI, an allosteric metabotropic glutamate receptor 1 antagonist with antipsychotic activity, on Fos expression in regions of the brain related to schizophrenia. Neuroscience. 2010 Jul 14;168(3):787-96. doi: 10.1016/j.neuroscience.2010.04.016. Epub 2010 Apr 18. PubMed PMID: 20399255.

2: Hikichi H, Nishino M, Fukushima M, Satow A, Maehara S, Kawamoto H, Ohta H. Pharmacological effects of metabotropic glutamate receptor ligands on prepulse inhibition in DBA/2J mice. Eur J Pharmacol. 2010 Aug 10;639(1-3):99-105. doi: 10.1016/j.ejphar.2010.03.046. Epub 2010 Apr 2. PubMed PMID: 20371235.

3: Satow A, Suzuki G, Maehara S, Hikichi H, Murai T, Murai T, Kawagoe-Takaki H, Hata M, Ito S, Ozaki S, Kawamoto H, Ohta H. Unique antipsychotic activities of the selective metabotropic glutamate receptor 1 allosteric antagonist 2-cyclopropyl-5-[1-(2-fluoro-3-pyridinyl)-5-methyl-1H-1,2,3-triazol-4-yl]-2,3-dih ydro-1H-isoindol-1-one. J Pharmacol Exp Ther. 2009 Jul;330(1):179-90. doi: 10.1124/jpet.109.151118. Epub 2009 Apr 9. PubMed PMID: 19359526.