CAY10397

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 525367

CAS#: 78028-01-0

Description: CAY10397 is a selective inhibitor of 15-hydroxy PGDH, significantly suppressing endogenous 11-oxo-ETE production with a corresponding increase in 11(R)-HETE.


Chemical Structure

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CAY10397
CAS# 78028-01-0

Theoretical Analysis

MedKoo Cat#: 525367
Name: CAY10397
CAS#: 78028-01-0
Chemical Formula: C17H16N2O5
Exact Mass: 328.1059
Molecular Weight: 328.324
Elemental Analysis: C, 62.19; H, 4.91; N, 8.53; O, 24.36

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: CAY10397

IUPAC/Chemical Name: 5-[[4-(Ethoxycarbonyl)phenyl]azo]-2-hydroxy-benzeneacetic acid

InChi Key: YYBSDOZYJSGLTH-VHEBQXMUSA-N

InChi Code: InChI=1S/C17H16N2O5/c1-2-24-17(23)11-3-5-13(6-4-11)18-19-14-7-8-15(20)12(9-14)10-16(21)22/h3-9,20H,2,10H2,1H3,(H,21,22)/b19-18+

SMILES Code: O=C(O)CC1=CC(/N=N/C2=CC=C(C(OCC)=O)C=C2)=CC=C1O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 328.324 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Liu X, Zhang S, Arora JS, Snyder NW, Shah SJ, Blair IA. 11-Oxoeicosatetraenoic acid is a cyclooxygenase-2/15-hydroxyprostaglandin dehydrogenase-derived antiproliferative eicosanoid. Chem Res Toxicol. 2011 Dec 19;24(12):2227-36. doi: 10.1021/tx200336f. Epub 2011 Sep 30. PubMed PMID: 21916491; PubMed Central PMCID: PMC3242474.

2: Wei C, Zhu P, Shah SJ, Blair IA. 15-oxo-Eicosatetraenoic acid, a metabolite of macrophage 15-hydroxyprostaglandin dehydrogenase that inhibits endothelial cell proliferation. Mol Pharmacol. 2009 Sep;76(3):516-25. doi: 10.1124/mol.109.057489. Epub 2009 Jun 17. PubMed PMID: 19535459; PubMed Central PMCID: PMC2730384.