WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 532774
CAS#: 867164-40-7
Description: TRC051384 is a inducer of heat shock protein Hsp70. It reduces stroke-associated neuronal injury and increases survival in a rat model of transient ischemic stroke. TRC051384 enhances Hsp72 expression in neurons and glial cells.
MedKoo Cat#: 532774
Name: TRC051384
CAS#: 867164-40-7
Chemical Formula: C25H31N5O4
Exact Mass: 465.2376
Molecular Weight: 465.55
Elemental Analysis: C, 64.50; H, 6.71; N, 15.04; O, 13.75
Synonym: TRC051384; TRC 051384; TRC-051384.
IUPAC/Chemical Name: N-[2-(4-Morpholinyl)ethyl]-N'-[4-[3-[6-(4-morpholinyl)-2-pyridinyl]-1-oxo-2-propen-1-yl]phenyl]urea
InChi Key: SQTSPANZQDCPLB-CMDGGOBGSA-N
InChi Code: InChI=1S/C25H31N5O4/c31-23(9-8-21-2-1-3-24(27-21)30-14-18-34-19-15-30)20-4-6-22(7-5-20)28-25(32)26-10-11-29-12-16-33-17-13-29/h1-9H,10-19H2,(H2,26,28,32)/b9-8+
SMILES Code: O=C(NC1=CC=C(C(/C=C/C2=NC(N3CCOCC3)=CC=C2)=O)C=C1)NCCN4CCOCC4
1. Mohanan et al (2011) Delayed intervention in experimental stroke with TRC051384--a small molecule HSP70 inducer. Neuropharmacology. 60 991. PMID: 21167846.