WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 407484

CAS#: 1422269-30-4

Description: ML18 is Bombesin receptor subtype 3 (BRS-3) antagonist (IC50 = 4.8 μM). ML-18 inhibits lung cancer growth. ML-18 inhibited the proliferation of lung cancer cells. ML-18 is a nonpeptide BRS-3 antagonist that should serve as a template to improve potency and selectivity.

Price and Availability

Size Price Shipping out time Quantity
100mg USD 1250 2 Weeks
200mg USD 1950 2 Weeks
500mg USD 2950 2 Weeks
1g USD 3850 2 Weeks
2g USD 5450 2 Weeks
5g USD 8650 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2021-01-25. Prices are subject to change without notice.

ML-18, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 407484
Name: ML-18
CAS#: 1422269-30-4
Chemical Formula: C32H35N5O5
Exact Mass: 569.2638
Molecular Weight: 569.662
Elemental Analysis: C, 67.47; H, 6.19; N, 12.29; O, 14.04

Synonym: ML-18; ML 18; ML18.

IUPAC/Chemical Name: (S)-3-(1H-indol-3-yl)-N-((1-(4-methoxyphenyl)cyclohexyl)methyl)-2-(3-(4-nitrophenyl)ureido)propanamide


InChi Code: InChI=1S/C32H35N5O5/c1-42-26-15-9-23(10-16-26)32(17-5-2-6-18-32)21-34-30(38)29(19-22-20-33-28-8-4-3-7-27(22)28)36-31(39)35-24-11-13-25(14-12-24)37(40)41/h3-4,7-16,20,29,33H,2,5-6,17-19,21H2,1H3,(H,34,38)(H2,35,36,39)/t29-/m0/s1

SMILES Code: O=C(NC1=CC=C([N+]([O-])=O)C=C1)N[C@H](C(NCC2(C3=CC=C(OC)C=C3)CCCCC2)=O)CC4=CNC5=C4C=CC=C5

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Moody TW, Mantey SA, Moreno P, Nakamura T, Lacivita E, Leopoldo M, Jensen RT.
ML-18 is a non-peptide bombesin receptor subtype-3 antagonist which inhibits lung
cancer growth. Peptides. 2015 Feb;64:55-61. doi: 10.1016/j.peptides.2014.12.005.
Epub 2014 Dec 30. PubMed PMID: 25554218; PubMed Central PMCID: PMC4397132.