WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 329661
Description: Carbimazole is used to treat hyperthyroidism. Carbimazole is a pro-drug as after absorption it is converted to the active form, methimazole. Methimazole prevents thyroid peroxidase enzyme from coupling and iodinating the tyrosine residues on thyroglobulin, hence reducing the production of the thyroid hormones T3 and T4 (thyroxine).
MedKoo Cat#: 329661
Chemical Formula: C7H10N2O2S
Exact Mass: 186.0463
Molecular Weight: 186.229
Elemental Analysis: C, 45.15; H, 5.41; N, 15.04; O, 17.18; S, 17.22
Synonym: Carbimazole; Neo-Tireol; Neomercazole; Thyrostat; Tyrazol;
IUPAC/Chemical Name: Ethyl 3-methyl-2-thioimidazoline-1-carboxylate
InChi Key: CFOYWRHIYXMDOT-UHFFFAOYSA-N
InChi Code: InChI=1S/C7H10N2O2S/c1-3-11-7(10)9-5-4-8(2)6(9)12/h4-5H,3H2,1-2H3
SMILES Code: O=C(N1C=CN(C)C1=S)OCC
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 186.229 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|