RS 39604 HCl

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 532589

CAS#: 167710-87-4(RS 39604 HCl); 172679-58-2(RS 39604).

Description: RS 39604 HCl is a potent and selective 5-HT4 antagonist, with a pKi of 9.1 at 5-HT4 receptors in guinea pig striatal membranes and greater than 1000-fold selectivity over 5-HT1A, 2C, 3 and D1, D2, M1, M2, AT1, B1 and α1C receptors.

Chemical Structure

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RS 39604 HCl
CAS# 167710-87-4(RS 39604 HCl); 172679-58-2(RS 39604).
Instruction

Theoretical Analysis

MedKoo Cat#: 532589
Name: RS 39604 HCl
CAS#: 167710-87-4(RS 39604 HCl); 172679-58-2(RS 39604).
Chemical Formula: C16H24Cl2N2O3
Exact Mass: 0.00
Molecular Weight: 363.280
Elemental Analysis: C, 52.90; H, 6.66; Cl, 19.52; N, 7.71; O, 13.21

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Related CAS #: 167710-87-4(RS 39604 HCl); 172679-58-2(RS 39604).  

Synonym: RS 39604; RS-39604; RS39604; RS 39604 HCl; RS 39604HCl.

IUPAC/Chemical Name: 1-[4-Amino-5-chloro-2-(3,5-dimethoxyphenyl)methyloxy]-3-[1-[2-methylsulphonylamino]ethyl]piperidin-4-yl]propan-1-one hydrochloride

InChi Key: QLZLBYYNMGQIAR-UHFFFAOYSA-N

InChi Code: InChI=1S/C16H23ClN2O3.ClH/c1-21-15-11-14(18)13(17)10-12(15)16(20)22-9-5-8-19-6-3-2-4-7-19;/h10-11H,2-9,18H2,1H3;1H

SMILES Code: O=C(OCCCN1CCCCC1)C2=CC(Cl)=C(N)C=C2OC.[H]Cl

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 363.28 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Hegde SS, Bonhaus DW, Johnson LG, Leung E, Clark RD, Eglen RM. RS 39604: a potent, selective and orally active 5-HT4 receptor antagonist. Br J Pharmacol. 1995 Jul;115(6):1087-95. PubMed PMID: 7582507; PubMed Central PMCID: PMC1908997.