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MedKoo CAT#: 532376

CAS#: 362612-47-3 (free base)

Description: NVP ACQ090 is a novel non-peptidic, potent and subtype-selective somatostatin sst(3) receptor antagonist.

Price and Availability

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Pricing updated 2020-08-09. Prices are subject to change without notice.

NVP ACQ090 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 532376
Name: NVP ACQ090
CAS#: 362612-47-3 (free base)
Chemical Formula: C30H40F2N4O2
Exact Mass: 526.3119
Molecular Weight: 526.67
Elemental Analysis: C, 68.42; H, 7.66; F, 7.21; N, 10.64; O, 6.08

Related CAS #: 649761-71-7 (tartrate)   362612-47-3 (free base)   1221509-66-5 (fumarate)    

Synonym: NVP ACQ090; NVPACQ090; NVP-ACQ090; ACQ090; ACQ-090; ACQ 090;

IUPAC/Chemical Name: [(4S,4aS,8aR)-2-[3-(6-methoxypyridin-3-yl)-2-methylpropyl]-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-4-yl]-[4-(3,4-difluorophenyl)piperazin-1-yl]methanone


InChi Code: InChI=1S/C30H40F2N4O2/c1-21(15-22-7-10-29(38-2)33-17-22)18-34-19-23-5-3-4-6-25(23)26(20-34)30(37)36-13-11-35(12-14-36)24-8-9-27(31)28(32)16-24/h7-10,16-17,21,23,25-26H,3-6,11-15,18-20H2,1-2H3/t21?,23-,25-,26+/m0/s1

SMILES Code: O=C([C@@H]1CN(CC(C)CC2=CC=C(OC)N=C2)C[C@]3([H])CCCC[C@]13[H])N4CCN(C5=CC=C(F)C(F)=C5)CC4

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Lehmann A, Kliewer A, Günther T, Nagel F, Schulz S. Identification of Phosphorylation Sites Regulating sst3 Somatostatin Receptor Trafficking. Mol Endocrinol. 2016 Jun;30(6):645-59. doi: 10.1210/me.2015-1244. Epub 2016 Apr 21. PubMed PMID: 27101376.

2: Einstein EB, Patterson CA, Hon BJ, Regan KA, Reddi J, Melnikoff DE, Mateer MJ, Schulz S, Johnson BN, Tallent MK. Somatostatin signaling in neuronal cilia is critical for object recognition memory. J Neurosci. 2010 Mar 24;30(12):4306-14. doi: 10.1523/JNEUROSCI.5295-09.2010. PubMed PMID: 20335466; PubMed Central PMCID: PMC3842454.

3: Troxler T, Hurth K, Schuh KH, Schoeffter P, Langenegger D, Enz A, Hoyer D. Decahydroisoquinoline derivatives as novel non-peptidic, potent and subtype-selective somatostatin sst(3) receptor antagonists. Bioorg Med Chem Lett. 2010 Mar 1;20(5):1728-34. doi: 10.1016/j.bmcl.2010.01.063. Epub 2010 Jan 21. PubMed PMID: 20137944.