NVP-2
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MedKoo CAT#: 532375

CAS#: 1263373-43-8

Description: NVP-2 is an inhibitor of the cyclin-dependent kinase, CDK9.


Price and Availability

Size Price Shipping out time Quantity
5mg USD 415 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2020-09-26. Prices are subject to change without notice.

NVP-2, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 532375
Name: NVP-2
CAS#: 1263373-43-8
Chemical Formula: C27H37ClN6O2
Exact Mass: 512.2667
Molecular Weight: 513.08
Elemental Analysis: C, 63.21; H, 7.27; Cl, 6.91; N, 16.38; O, 6.24


Synonym: NVP-2 ; NVP 2; NVP2.

IUPAC/Chemical Name: 4-({[6-(5-chloro-2-{[(1r,4r)-4-{[(2R)-1-methoxypropan-2-yl]amino}cyclohexyl]amino}pyridin-4-yl)pyridin-2-yl]amino}methyl)oxane-4-carbonitrile

InChi Key: XWQVQSXLXAXOPJ-NJDAHSKKSA-N

InChi Code: InChI=1S/C27H37ClN6O2/c1-19(16-35-2)32-20-6-8-21(9-7-20)33-26-14-22(23(28)15-30-26)24-4-3-5-25(34-24)31-18-27(17-29)10-12-36-13-11-27/h3-5,14-15,19-21,32H,6-13,16,18H2,1-2H3,(H,30,33)(H,31,34)/t19-,20-,21-/m1/s1

SMILES Code: N#CC1(CNC2=NC(C3=CC(N[C@H]4CC[C@H](N[C@H](C)COC)CC4)=NC=C3Cl)=CC=C2)CCOCC1


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001


References

1. Barsanti PA et al.. (2011) Pyridine and pyrazine derivatives as protein kinase modulators.
Patent number: WO2011012661.