WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 407448
CAS#: 79183-19-0
Description: MDK83190, also known as Apoptosis Activator 2, is an Apoptosis Activator. MDK83190 has CAS#79183-19-0, in which the last 5 digit was used for its name for easier communication. MDK83190 has been shown to induce apoptosis in leukemia cells (IC50 = 4-9 μM) .
MedKoo Cat#: 407448
Name: MDK83190
CAS#: 79183-19-0
Chemical Formula: C15H9Cl2NO2
Exact Mass: 305.001
Molecular Weight: 306.142
Elemental Analysis: C, 58.85; H, 2.96; Cl, 23.16; N, 4.58; O, 10.45
Synonym: Apoptosis Activator 2; AAII; N-(3,4-dichlorobenzyl) Isatin. MDK83190; MDK-83190; MDK 83190.
IUPAC/Chemical Name: 1-[(3,4-dichlorophenyl)methyl]-1H-indole-2,3-dione
InChi Key: KGRJPLRFGLMQMV-UHFFFAOYSA-N
InChi Code: InChI=1S/C15H9Cl2NO2/c16-11-6-5-9(7-12(11)17)8-18-13-4-2-1-3-10(13)14(19)15(18)20/h1-7H,8H2
SMILES Code: O=C1N(CC2=CC=C(Cl)C(Cl)=C2)C3=C(C=CC=C3)C1=O
1: Nguyen JT, Wells JA. Direct activation of the apoptosis machinery as a
mechanism to target cancer cells. Proc Natl Acad Sci U S A. 2003 Jun
24;100(13):7533-8. Epub 2003 Jun 13. PubMed PMID: 12808146; PubMed Central PMCID:
PMC164621.