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SB-756050
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 528518

CAS#: 447410-57-3

Description: SB-756050 is a G protein-coupled bile acid receptor 1 (GPBAR1) agonist potentially for the treatment of type 2 diabetes.


Price and Availability

Size Price Shipping out time Quantity
100mg USD 350 2 Weeks
250mg USD 750 2 Weeks
Inquire bulk and customized quantity
Pricing updated 2021-01-26. Prices are subject to change without notice.

SB-756050, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received..


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 528518
Name: SB-756050
CAS#: 447410-57-3
Chemical Formula: C21H28N2O8S2
Exact Mass: 500.1287
Molecular Weight: 500.581
Elemental Analysis: C, 50.39; H, 5.64; N, 5.60; O, 25.57; S, 12.81


Synonym: SB-756050; SB 756050; SB756050

IUPAC/Chemical Name: 1,4-bis((3,4-dimethoxyphenyl)sulfonyl)-1,4-diazepane

InChi Key: GJUFPAZNBPFNRI-UHFFFAOYSA-N

InChi Code: InChI=1S/C21H28N2O8S2/c1-28-18-8-6-16(14-20(18)30-3)32(24,25)22-10-5-11-23(13-12-22)33(26,27)17-7-9-19(29-2)21(15-17)31-4/h6-9,14-15H,5,10-13H2,1-4H3

SMILES Code: O=S(N1CCN(S(=O)(C2=CC=C(OC)C(OC)=C2)=O)CCC1)(C3=CC=C(OC)C(OC)=C3)=O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001


References

1: Hodge RJ, Lin J, Vasist Johnson LS, Gould EP, Bowers GD, Nunez DJ; SB-756050 Project Team.. Safety, Pharmacokinetics, and Pharmacodynamic Effects of a Selective TGR5 Agonist, SB-756050, in Type 2 Diabetes. Clin Pharmacol Drug Dev. 2013 Jul;2(3):213-22. doi: 10.1002/cpdd.34. Epub 2013 May 14. PubMed PMID: 27121782.