NGB2904 HCl

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MedKoo CAT#: 532347

CAS#: 189060-98-8 (HCl)

Description: NGB2904 is a potent and selective dopamine D3 receptor antagonist (Ki values are 1.4, 217, 223, 642, > 5000, > 10000 and > 10000 nM for D3, D2, 5-HT2, α1, D4, D1 and D5 receptors respectively). NGB2904 potently antagonizes quinpirole-stimulated mitogenesis (IC50 = 6.8 nM)

Price and Availability

Size Price Shipping out time Quantity
5mg USD 210 2 Weeks
10mg USD 385 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2020-10-29. Prices are subject to change without notice.

NGB2904 HCl, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 532347
Name: NGB2904 HCl
CAS#: 189060-98-8 (HCl)
Chemical Formula: C28H30Cl3N3O
Exact Mass: 493.1688
Molecular Weight: 530.918
Elemental Analysis: C, 63.34; H, 5.70; Cl, 20.03; N, 7.91; O, 3.01

Related CAS #: 189060-98-8 (HCl)   189061-11-8 (free base)    

Synonym: NGB2904; NGB 2904; NGB-2904.

IUPAC/Chemical Name: N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-9H-fluorene-2-carboxamide hydrochloride


InChi Code: InChI=1S/C28H29Cl2N3O.ClH/c29-25-8-5-9-26(27(25)30)33-16-14-32(15-17-33)13-4-3-12-31-28(34)21-10-11-24-22(19-21)18-20-6-1-2-7-23(20)24;/h1-2,5-11,19H,3-4,12-18H2,(H,31,34);1H


Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Hussein N, Amawi H, Karthikeyan C, Hall FS, Mittal R, Trivedi P, Ashby CR Jr, Tiwari AK. The dopamine D(3) receptor antagonists PG01037, NGB2904, SB277011A, and U99194 reverse ABCG2 transporter-mediated drug resistance in cancer cell lines. Cancer Lett. 2017 Mar 18. pii: S0304-3835(17)30179-9. doi: 10.1016/j.canlet.2017.03.015. [Epub ahead of print] PubMed PMID: 28323029.