NE21650

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MedKoo CAT#: 532320

CAS#: 427899-21-6

Description: NE21650 is a bisphosphonate that inhibits isopentenyl diphosphate isomerase and farnesyl diphosphate synthase.


Price and Availability

Size Price Shipping out time Quantity
Inquire bulk and customized quantity

Pricing updated 2020-09-28. Prices are subject to change without notice.

NE21650 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 532320
Name: NE21650
CAS#: 427899-21-6
Chemical Formula: C8H13NO7P2
Exact Mass: 297.0167
Molecular Weight: 297.14
Elemental Analysis: C, 32.34; H, 4.41; N, 4.71; O, 37.69; P, 20.85


Synonym: NE21650; NE 21650; NE-21650.

IUPAC/Chemical Name: [2-(2-aminophenyl)-1-hydroxy-1-phosphonoethyl]phosphonic acid

InChi Key: VJXYJONFUZXZJZ-UHFFFAOYSA-N

InChi Code: InChI=1S/C8H13NO7P2/c9-7-4-2-1-3-6(7)5-8(10,17(11,12)13)18(14,15)16/h1-4,10H,5,9H2,(H2,11,12,13)(H2,14,15,16)

SMILES Code: O=P(C(O)(P(O)(O)=O)CC1=CC=CC=C1N)(O)O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001


References

1: van Beek ER, Cohen LH, Leroy IM, Ebetino FH, Löwik CW, Papapoulos SE. Differentiating the mechanisms of antiresorptive action of nitrogen containing bisphosphonates. Bone. 2003 Nov;33(5):805-11. PubMed PMID: 14623056.

2: Thompson K, Dunford JE, Ebetino FH, Rogers MJ. Identification of a bisphosphonate that inhibits isopentenyl diphosphate isomerase and farnesyl diphosphate synthase. Biochem Biophys Res Commun. 2002 Jan 18;290(2):869-73. PubMed PMID: 11785983.