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MedKoo CAT#: 528513

CAS#: 104340-52-5

Description: NC-1300-B is a proton pump inhibitor potentially for treatment of gastric ulcer. H(+)-K(+)-ATPase inhibition with NC-1300-B causes profound renal vasodilation and inhibition of renin release without affecting regulation of GFR.

Price and Availability

Size Price Shipping out time Quantity
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Pricing updated 2020-10-30. Prices are subject to change without notice.

NC-1300-B is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 528513
Name: NC-1300-B
CAS#: 104340-52-5
Chemical Formula: C17H19N3OS
Exact Mass: 313.1249
Molecular Weight: 313.419
Elemental Analysis: C, 65.15; H, 6.11; N, 13.41; O, 5.10; S, 10.23

Synonym: NC-1300-B; NC1300B; NC 1300 B

IUPAC/Chemical Name: N,N-dimethyl-2-(((6-methyl-1H-benzo[d]imidazol-2-yl)sulfinyl)methyl)aniline


InChi Code: InChI=1S/C17H19N3OS/c1-12-8-9-14-15(10-12)19-17(18-14)22(21)11-13-6-4-5-7-16(13)20(2)3/h4-10H,11H2,1-3H3,(H,18,19)


Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Lin H, Young DB. Reduction in renin release and renal vascular resistance by H(+)-K(+)-ATPase inhibition. Am J Physiol. 1997 Sep;273(3 Pt 2):F457-62. PubMed PMID: 9321920.

2: Rhoden KJ, Tallini G, Douglas JS. H+-K+ ATPase inhibitors cause relaxation of guinea pig and human airway smooth muscle in vitro. J Pharmacol Exp Ther. 1996 Mar;276(3):897-903. PubMed PMID: 8786567.

3: McCabe RD, Young DB. Evidence of a K(+)-H(+)-ATPase in vascular smooth muscle cells. Am J Physiol. 1992 Jun;262(6 Pt 2):H1955-8. PubMed PMID: 1320341.

4: Okabe S, Akimoto Y, Yamasaki S, Nagai H. Effects of NC-1300-B, a new benzimidazole derivative, on hog gastric H+, K+-ATPase, gastric acid secretion and HCl.ethanol-induced gastric lesions in rats. Dig Dis Sci. 1988 Nov;33(11):1425-34. PubMed PMID: 2846250.