WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 532175
CAS#: 80558-61-8
Description: MB-28767 is a prostaglandin E2 (PGE2) receptor agonist.
MedKoo Cat#: 532175
Name: MB-28767
CAS#: 80558-61-8
Chemical Formula: C22H30O5
Exact Mass: 374.2093
Molecular Weight: 374.48
Elemental Analysis: C, 70.56; H, 8.08; O, 21.36
This product is not in stock, which may be available by custom synthesis.
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Synonym: MB-28767; MB 28767; MB28767; M&B 28767.
IUPAC/Chemical Name: 7-[(1R,2R)-2-[(E,3R)-3-hydroxy-4-(phenoxy)but-1-enyl]-5-oxocyclopentyl]heptanoic acid
InChi Key: NZGFSDWJUZOAAX-KAVAACISSA-N
InChi Code: InChI=1S/C22H30O5/c23-18(16-27-19-8-4-3-5-9-19)14-12-17-13-15-21(24)20(17)10-6-1-2-7-11-22(25)26/h3-5,8-9,12,14,17-18,20,23H,1-2,6-7,10-11,13,15-16H2,(H,25,26)/b14-12+/t17-,18+,20+/m0/s1
SMILES Code: O=C(O)CCCCCC[C@@H]1[C@@H](/C=C/[C@@H](O)COC2=CC=CC=C2)CCC1=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 374.48 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Minami T, Nishihara I, Uda R, Ito S, Hyodo M, Hayaishi O. Characterization of EP-receptor subtypes involved in allodynia and hyperalgesia induced by intrathecal administration of prostaglandin E2 to mice. Br J Pharmacol. 1994 Jul;112(3):735-40. PubMed PMID: 7921597; PubMed Central PMCID: PMC1910214.