eCF-309

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 407417

CAS#: 2001571-40-8

Description: eCF-309 is a potent mTOR inhibitor (IC50 = 15 nM).


Price and Availability

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eCF-309 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 407417
Name: eCF-309
CAS#: 2001571-40-8
Chemical Formula: C18H21N7O3
Exact Mass: 383.1706
Molecular Weight: 383.412
Elemental Analysis: C, 56.39; H, 5.52; N, 25.57; O, 12.52


Synonym: eCF-309; eCF 309; eCF309; ECF-309; ECF 309; ECF309.

IUPAC/Chemical Name: 3-(2-Amino-5-benzoxazolyl)-1-(2,2-diethoxyethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

InChi Key: PSICWGWNIOOULV-UHFFFAOYSA-N

InChi Code: InChI=1S/C18H21N7O3/c1-3-26-13(27-4-2)8-25-17-14(16(19)21-9-22-17)15(24-25)10-5-6-12-11(7-10)23-18(20)28-12/h5-7,9,13H,3-4,8H2,1-2H3,(H2,20,23)(H2,19,21,22)

SMILES Code: NC1=C2C(N(CC(OCC)OCC)N=C2C3=CC=C(OC(N)=N4)C4=C3)=NC=N1


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

Fraser et al (2016) eCF309: a potent, selective and cell-permeable mTOR inhibitor Med.Chem.Commun. 4 471.