WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 530531
CAS#: 1393124-08-7
Description: PF-06291874 is a glucagon receptor antagonist nd potentially usefully for patients with type 2 diabetes mellitus. PF-06291874 was well tolerated, has a pharmacokinetic profile suitable for once-daily dosing, and results in reductions in glucose with minimal risk of hypoglycaemia.
MedKoo Cat#: 530531
Name: PF-06291874
CAS#: 1393124-08-7
Chemical Formula: C26H28F3N3O4
Exact Mass: 503.2032
Molecular Weight: 503.5222
Elemental Analysis: C, 62.02; H, 5.61; F, 11.32; N, 8.35; O, 12.71
Synonym: PF-06291874; PF 06291874; PF06291874; PF-6291874; PF 6291874; PF6291874.
IUPAC/Chemical Name: (S)-3-(4-(1-(3,5-dimethyl-4-(4-(trifluoromethyl)-1H-pyrazol-1-yl)phenoxy)butyl)benzamido)propanoic acid
InChi Key: IBDYYOQKQCCSDP-QFIPXVFZSA-N
InChi Code: InChI=1S/C26H28F3N3O4/c1-4-5-22(18-6-8-19(9-7-18)25(35)30-11-10-23(33)34)36-21-12-16(2)24(17(3)13-21)32-15-20(14-31-32)26(27,28)29/h6-9,12-15,22H,4-5,10-11H2,1-3H3,(H,30,35)(H,33,34)/t22-/m0/s1
SMILES Code: O=C(O)CCNC(C1=CC=C([C@@H](OC2=CC(C)=C(C(C)=C2)N3C=C(C=N3)C(F)(F)F)CCC)C=C1)=O