WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 532105

CAS#: 634193-54-7

Description: L-902,688 is a highly potent agonist of the human PGE2 receptor, EP4. L902688 demonstrates a Ki value of 0.38 nM and an EC50 value of 0.6 nM and is >4,000-fold selective for EP4 over other EP and prostanoid receptors. Note: This product is supplied as methanol solution

Chemical Structure

CAS# 634193-54-7

Theoretical Analysis

MedKoo Cat#: 532105
Name: L902688
CAS#: 634193-54-7
Chemical Formula: C21H27F2N5O2
Exact Mass: 419.2133
Molecular Weight: 419.48
Elemental Analysis: C, 60.13; H, 6.49; F, 9.06; N, 16.70; O, 7.63

Price and Availability

Size Price Availability Quantity
1.0mg USD 350.0 2 Weeks
5.0mg USD 950.0 2 Weeks
10.0mg USD 1650.0 2 Weeks
Bulk inquiry

Synonym: L902688; L-902688; L 902688.

IUPAC/Chemical Name: (5R)-5-[(1E,3R)-4,4-difluoro-3-hydroxy-4-phenylbut-1-en-1-yl]-1-[6-(1H-1,2,3,4-tetrazol-5-yl)hexyl]pyrrolidin-2-one


InChi Code: InChI=1S/C21H27F2N5O2/c22-21(23,16-8-4-3-5-9-16)18(29)13-11-17-12-14-20(30)28(17)15-7-2-1-6-10-19-24-26-27-25-19/h3-5,8-9,11,13,17-18,29H,1-2,6-7,10,12,14-15H2,(H,24,25,26,27)/b13-11+/t17-,18+/m0/s1

SMILES Code: O=C1N(CCCCCCC2=NN=NN2)[C@@H](/C=C/[C@@H](O)C(F)(F)C3=CC=CC=C3)CC1

Appearance: supplied as methanol solution.

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 419.48 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Dilution Calculator

Calculate the dilution required to prepare a stock solution.

1: Malty RH, Hudmon A, Fehrenbacher JC, Vasko MR. Long-term exposure to PGE2 causes homologous desensitization of receptor-mediated activation of protein kinase A. J Neuroinflammation. 2016 Jul 11;13(1):181. doi: 10.1186/s12974-016-0645-0. PubMed PMID: 27400965; PubMed Central PMCID: PMC4940832.


1.0mg / USD 350.0