WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 532101

CAS#: 286456-42-6

Description: L838417 is a GABAA receptor modulator.

Chemical Structure

CAS# 286456-42-6

Theoretical Analysis

MedKoo Cat#: 532101
Name: L838417
CAS#: 286456-42-6
Chemical Formula: C19H19F2N7O
Exact Mass: 399.1619
Molecular Weight: 399.41
Elemental Analysis: C, 57.14; H, 4.80; F, 9.51; N, 24.55; O, 4.01

Price and Availability

Size Price Availability Quantity
5.0mg USD 380.0 2 Weeks
25.0mg USD 1130.0 2 Weeks
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Synonym: L838417; L 838417; L-838417.

IUPAC/Chemical Name: 5-({[7-tert-butyl-3-(2,5-difluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]oxy}methyl)-1-methyl-1H-1,2,4-triazole


InChi Code: InChI=1S/C19H19F2N7O/c1-19(2,3)13-8-15-24-25-17(12-7-11(20)5-6-14(12)21)28(15)26-18(13)29-9-16-22-10-23-27(16)4/h5-8,10H,9H2,1-4H3


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 399.41 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Munro G, Ahring PK, Mirza NR. Developing analgesics by enhancing spinal inhibition after injury: GABAA receptor subtypes as novel targets. Trends Pharmacol Sci. 2009 Sep;30(9):453-9. doi: 10.1016/j.tips.2009.06.004. Review. PubMed PMID: 19729210.


5.0mg / USD 380.0