WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 532100
Description: L-826266 is a EP(1) receptor antagonist.
MedKoo Cat#: 532100
Chemical Formula: C27H21BrClNO4S
Exact Mass: 569.0063
Molecular Weight: 570.88
Elemental Analysis: C, 56.81; H, 3.71; Br, 14.00; Cl, 6.21; N, 2.45; O, 11.21; S, 5.62
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
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Synonym: L-826266; L 826266; L826266.
IUPAC/Chemical Name: (E)-N-(5-bromo-2-methoxyphenyl)sulfonyl-3-[5-chloro-2-(naphthalen-2-ylmethyl)phenyl]prop-2-enamide
InChi Key: DYXFUJYHEDGCLS-UKTHLTGXSA-N
InChi Code: InChI=1S/C27H21BrClNO4S/c1-34-25-12-10-23(28)17-26(25)35(32,33)30-27(31)13-9-22-16-24(29)11-8-21(22)15-18-6-7-19-4-2-3-5-20(19)14-18/h2-14,16-17H,15H2,1H3,(H,30,31)/b13-9+
SMILES Code: O=C(NS(=O)(C1=CC(Br)=CC=C1OC)=O)/C=C/C2=CC(Cl)=CC=C2CC3=CC=C4C=CC=CC4=C3
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 570.88 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Kozłowska H, Baranowska-Kuczko M, Schlicker E, Kozłowski M, Zakrzeska A, Grzęda E, Malinowska B. EP₃ receptor-mediated contraction of human pulmonary arteries and inhibition of neurogenic tachycardia in pithed rats. Pharmacol Rep. 2012;64(6):1526-36. PubMed PMID: 23406763.