WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 532094
CAS#: L-796449 sodium
Description: L-796449 is a PPAR-gamma agonist.
MedKoo Cat#: 532094
Name: L-796449 sodium
CAS#: L-796449 sodium
Chemical Formula: C28H26ClNaO4S
Exact Mass: 494.1319
Molecular Weight: 517.01
Elemental Analysis: C, 65.05; H, 5.07; Cl, 6.86; Na, 4.45; O, 12.38; S, 6.20
This product is not in stock, which may be available by custom synthesis.
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Synonym: L-796449; L 796449; L796449.
IUPAC/Chemical Name: sodium 2-[3-chloro-4-[3-[(3-phenyl-7-propyl-1-benzofuran-6-yl)oxy]propylsulfanyl]phenyl]acetate
InChi Key: DFGIWDSZLMUKGS-UHFFFAOYSA-M
InChi Code: InChI=1S/C28H27ClO4S.Na/c1-2-7-22-25(12-11-21-23(18-33-28(21)22)20-8-4-3-5-9-20)32-14-6-15-34-26-13-10-19(16-24(26)29)17-27(30)31;/h3-5,8-13,16,18H,2,6-7,14-15,17H2,1H3,(H,30,31);/q;+1/p-1
SMILES Code: O=C([O-])CC1=CC=C(SCCCOC2=C(CCC)C3=C(C=C2)C(C4=CC=CC=C4)=CO3)C(Cl)=C1.[Na+]
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 517.01 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Pereira MP, Hurtado O, Cárdenas A, Alonso-Escolano D, Boscá L, Vivancos J, Nombela F, Leza JC, Lorenzo P, Lizasoain I, Moro MA. The nonthiazolidinedione PPARgamma agonist L-796,449 is neuroprotective in experimental stroke. J Neuropathol Exp Neurol. 2005 Sep;64(9):797-805. PubMed PMID: 16141790.
2: Castrillo A, Mojena M, Hortelano S, Boscá L. Peroxisome proliferator-activated receptor-gamma-independent inhibition of macrophage activation by the non-thiazolidinedione agonist L-796,449. Comparison with the effects of 15-deoxy-delta(12,14)-prostaglandin J(2). J Biol Chem. 2001 Sep 7;276(36):34082-8. PubMed PMID: 11438523.