WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 532091
Description: L-779,976 is a somatostatin receptor agonist.
MedKoo Cat#: 532091
Chemical Formula: C33H43N7O3
Exact Mass: 585.3427
Molecular Weight: 585.75
Elemental Analysis: C, 67.67; H, 7.40; N, 16.74; O, 8.19
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
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Note: Price will be listed if it is available in the future.
Synonym: L-779,976; L 779,976; L779,976; L-779976; L 779976; L779976.
IUPAC/Chemical Name: N-((2R,3S)-1-((((1R,3S)-3-(aminomethyl)cyclohexyl)methyl)amino)-3-(1H-indol-3-yl)-1-oxobutan-2-yl)-4-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidine-1-carboxamide
InChi Key: DDVPVAOEMZRZQU-CXDLDTBJSA-N
InChi Code: InChI=1S/C33H43N7O3/c1-21(26-20-35-27-10-3-2-9-25(26)27)30(31(41)36-19-23-8-6-7-22(17-23)18-34)38-32(42)39-15-13-24(14-16-39)40-29-12-5-4-11-28(29)37-33(40)43/h2-5,9-12,20-24,30,35H,6-8,13-19,34H2,1H3,(H,36,41)(H,37,43)(H,38,42)/t21-,22-,23+,30+/m0/s1
SMILES Code: O=C(NC[C@H]1C[C@@H](CN)CCC1)[C@H](NC(N2CCC(N3C4=CC=CC=C4NC3=O)CC2)=O)[C@@H](C)C5=CNC6=C5C=CC=C6
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 585.75 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Yeung M, Treit D. The anxiolytic effects of somatostatin following intra-septal and intra-amygdalar microinfusions are reversed by the selective sst2 antagonist PRL2903. Pharmacol Biochem Behav. 2012 Mar;101(1):88-92. doi: 10.1016/j.pbb.2011.12.012. PubMed PMID: 22210489.
2: Aourz N, De Bundel D, Stragier B, Clinckers R, Portelli J, Michotte Y, Smolders I. Rat hippocampal somatostatin sst3 and sst4 receptors mediate anticonvulsive effects in vivo: indications of functional interactions with sst2 receptors. Neuropharmacology. 2011 Dec;61(8):1327-33. doi: 10.1016/j.neuropharm.2011.08.003. PubMed PMID: 21854790.