WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 532087
CAS#: 227002-04-2
Description: L-764406 is a partial agonist of human peroxisome proliferator-activated receptor gamma.
MedKoo Cat#: 532087
Name: L-764406
CAS#: 227002-04-2
Chemical Formula: C15H11ClN2O2S
Exact Mass: 318.023
Molecular Weight: 318.78
Elemental Analysis: C, 56.52; H, 3.48; Cl, 11.12; N, 8.79; O, 10.04; S, 10.06
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
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Synonym: L-764406; L 764406; L764406.
IUPAC/Chemical Name: 2-chloro-3-(phenylsulfonylmethyl)quinoxaline
InChi Key: AMNQYONRCBZMGT-UHFFFAOYSA-N
InChi Code: InChI=1S/C15H11ClN2O2S/c16-15-14(17-12-8-4-5-9-13(12)18-15)10-21(19,20)11-6-2-1-3-7-11/h1-9H,10H2
SMILES Code: O=S(CC1=NC2=CC=CC=C2N=C1Cl)(C3=CC=CC=C3)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 318.78 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Elbrecht A, Chen Y, Adams A, Berger J, Griffin P, Klatt T, Zhang B, Menke J, Zhou G, Smith RG, Moller DE. L-764406 is a partial agonist of human peroxisome proliferator-activated receptor gamma. The role of Cys313 in ligand binding. J Biol Chem. 1999 Mar 19;274(12):7913-22. PubMed PMID: 10075686.
