L659989
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 532063

CAS#: 113787-28-3

Description: L659989 is a PAF receptor antagonist.


Price and Availability

Size
Price

5mg
USD 1010
Size
Price

10mg
USD 1980
Size
Price

100mg
USD 3020

L659989, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 532063
Name: L659989
CAS#: 113787-28-3
Chemical Formula: C24H32O8S
Exact Mass: 480.1818
Molecular Weight: 480.57
Elemental Analysis: C, 59.98; H, 6.71; O, 26.63; S, 6.67


Synonym: L659989; L 659989; L-659989.

IUPAC/Chemical Name: (2S,5S)-2-(3-methoxy-5-methylsulfonyl-4-propoxyphenyl)-5-(3,4,5-trimethoxyphenyl)oxolane

InChi Key: NZWPFJNQOZFEDT-ROUUACIJSA-N

InChi Code: InChI=1S/C24H32O8S/c1-7-10-31-24-21(29-4)13-16(14-22(24)33(6,25)26)18-9-8-17(32-18)15-11-19(27-2)23(30-5)20(12-15)28-3/h11-14,17-18H,7-10H2,1-6H3/t17-,18-/m0/s1

SMILES Code: COC1=C(OC)C(OC)=CC([C@@H]2CC[C@@H](C3=CC(S(=O)(C)=O)=C(OCCC)C(OC)=C3)O2)=C1


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Chen J, Giris N. Species differences in PAF receptor binding in the lungs between hamster and guinea pig. J Lipid Mediat Cell Signal. 1997 Jun;16(2):63-74. PubMed PMID: 9172049.

2: Lin Y, Jamieson D. Are leukotrienes or PAF involved in hyperbaric oxygen toxicity? Agents Actions. 1993 Jan;38(1-2):66-75. PubMed PMID: 8386902.

3: Lefkowith JB, Morrison A, Lee V, Rogers M. Manipulation of the acute inflammatory response by dietary polyunsaturated fatty acid modulation. J Immunol. 1990 Sep 1;145(5):1523-9. PubMed PMID: 2166763.