WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 532061
Description: L-644,698 is a novel selective human prostanoid DP receptor agonist.
MedKoo Cat#: 532061
Chemical Formula: C21H31NO4S
Exact Mass: 393.1974
Molecular Weight: 393.54
Elemental Analysis: C, 64.09; H, 7.94; N, 3.56; O, 16.26; S, 8.15
This product is not in stock, which may be available by custom synthesis.
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Synonym: L-644,698; L 644,698; L644,698.
IUPAC/Chemical Name: 4-[3-[3-(3-hydroxyoctyl)-4-oxo-1,3-thiazolidin-2-yl]propyl]benzoic acid
InChi Key: NDAXAJCKSWCWQI-UHFFFAOYSA-N
InChi Code: InChI=1S/C21H31NO4S/c1-2-3-4-7-18(23)13-14-22-19(24)15-27-20(22)8-5-6-16-9-11-17(12-10-16)21(25)26/h9-12,18,20,23H,2-8,13-15H2,1H3,(H,25,26)
SMILES Code: O=C(O)C1=CC=C(CCCC(N2CCC(O)CCCCC)SCC2=O)C=C1
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 393.54 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Wright DH, Ford-Hutchinson AW, Chadee K, Metters KM. The human prostanoid DP receptor stimulates mucin secretion in LS174T cells. Br J Pharmacol. 2000 Dec;131(8):1537-45. PubMed PMID: 11139429; PubMed Central PMCID: PMC1572485.
2: Wright DH, Nantel F, Metters KM, Ford-Hutchinson AW. A novel biological role for prostaglandin D2 is suggested by distribution studies of the rat DP prostanoid receptor. Eur J Pharmacol. 1999 Jul 14;377(1):101-15. PubMed PMID: 10448933.
3: Wright DH, Metters KM, Abramovitz M, Ford-Hutchinson AW. Characterization of the recombinant human prostanoid DP receptor and identification of L-644,698, a novel selective DP agonist. Br J Pharmacol. 1998 Apr;123(7):1317-24. PubMed PMID: 9579725; PubMed Central PMCID: PMC1565289.