WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 531965
Description: ICI 169369 is a 5-HT2/5-HT1C antagonist, that can evoke endothelium-dependent relaxation in rabbit aorta.
MedKoo Cat#: 531965
Name: ICI 169369
Chemical Formula: C19H20N2S
Exact Mass: 308.1347
Molecular Weight: 308.44
Elemental Analysis: C, 73.99; H, 6.54; N, 9.08; S, 10.39
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Synonym: ICI 169369; ICI169369; ICI-169369.
IUPAC/Chemical Name: N,N-dimethyl-2-(3-phenylquinolin-2-yl)sulfanylethanamine
InChi Key: HYOLQGVNMQNERE-UHFFFAOYSA-N
InChi Code: InChI=1S/C19H20N2S/c1-21(2)12-13-22-19-17(15-8-4-3-5-9-15)14-16-10-6-7-11-18(16)20-19/h3-11,14H,12-13H2,1-2H3
SMILES Code: CN(C)CCSC1=NC2=CC=CC=C2C=C1C3=CC=CC=C3
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 308.44 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Pires JG, Ramage AG, Jacobs M. ICI 169,369, A 5-HT2/5-HT1C antagonist, that can evoke endothelium-dependent relaxation in rabbit aorta. J Auton Pharmacol. 1993 Aug;13(4):249-55. PubMed PMID: 8408095.
2: Nielsen TH, Tfelt-Hansen P. No effect of the 5HT2-antagonist ICI 169,369 on systolic, ergotamine-induced blood pressure changes in man. Pharmacol Toxicol. 1993 Sep;73(3):133-6. PubMed PMID: 8265515.