FG-5893

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 531781

CAS#: 150527-23-4

Description: FG-5893 is a novel 5-HT1A agonist/5-HT2 antagonist. FG-5893 is a potential anxiolytic drug.


Chemical Structure

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FG-5893
CAS# 150527-23-4

Theoretical Analysis

MedKoo Cat#: 531781
Name: FG-5893
CAS#: 150527-23-4
Chemical Formula: C27H29F2N3O2
Exact Mass: 465.22
Molecular Weight: 465.540
Elemental Analysis: C, 69.66; H, 6.28; F, 8.16; N, 9.03; O, 6.87

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: FG-5893; FG 5893; FG5893.

IUPAC/Chemical Name: methyl 2-[4-[4,4-bis(4-fluorophenyl)butyl]piperazin-1-yl]pyridine-3-carboxylate

InChi Key: NDCPNKXUTJGQQC-UHFFFAOYSA-N

InChi Code: InChI=1S/C27H29F2N3O2/c1-34-27(33)25-4-2-14-30-26(25)32-18-16-31(17-19-32)15-3-5-24(20-6-10-22(28)11-7-20)21-8-12-23(29)13-9-21/h2,4,6-14,24H,3,5,15-19H2,1H3

SMILES Code: O=C(C1=CC=CN=C1N2CCN(CCCC(C3=CC=C(F)C=C3)C4=CC=C(F)C=C4)CC2)OC

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 465.54 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Lankford MF, Björk AK, Myers RD. Differential efficacy of serotonergic drugs FG5974, FG5893, and amperozide in reducing alcohol drinking in P rats. Alcohol. 1996 Jul-Aug;13(4):399-404. PubMed PMID: 8836330.

2: Long TA, Kalmus GW, Björk A, Myers RD. Alcohol intake in high alcohol drinking (HAD) rats is suppressed by FG5865, a novel 5-HT1A agonist/5-HT2 antagonist. Pharmacol Biochem Behav. 1996 Jan;53(1):33-40. PubMed PMID: 8848457.