WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 529415

CAS#: 573981-31-4

Description: Cannabinor, also known as PRS-211375 and PRS 375, is a cannabinoid CB2 agonist potentially for the treatment of partial urethral obstruction.

Chemical Structure

CAS# 573981-31-4

Theoretical Analysis

MedKoo Cat#: 529415
Name: Cannabinor
CAS#: 573981-31-4
Chemical Formula: C28H38O6
Exact Mass: 470.2668
Molecular Weight: 470.6
Elemental Analysis: C, 71.46; H, 8.14; O, 20.40

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: PRS-211375; PRS211375; PRS 211375; PRS-375; PRS375; PRS 375; Cannabinor

IUPAC/Chemical Name: (E)-4-(2-((1S,2S,5S)-6,6-dimethyl-4-oxobicyclo[3.1.1]heptan-2-yl)-3-hydroxy-5-(2-methyloctan-2-yl)phenoxy)-4-oxobut-2-enoic acid


InChi Code: InChI=1S/C28H38O6/c1-6-7-8-9-12-27(2,3)17-13-22(30)26(23(14-17)34-25(33)11-10-24(31)32)18-15-21(29)20-16-19(18)28(20,4)5/h10-11,13-14,18-20,30H,6-9,12,15-16H2,1-5H3,(H,31,32)/b11-10+/t18-,19-,20+/m0/s1

SMILES Code: O=C(OC1=CC(C(C)(C)CCCCCC)=CC(O)=C1[C@@H](C2)[C@@](C3)([H])C(C)(C)[C@@]3([H])C2=O)/C=C/C(O)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 470.6 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Gratzke C, Streng T, Stief CG, Downs TR, Alroy I, Rosenbaum JS, Andersson KE, Hedlund P. Effects of cannabinor, a novel selective cannabinoid 2 receptor agonist, on bladder function in normal rats. Eur Urol. 2010 Jun;57(6):1093-100. doi: 10.1016/j.eururo.2010.02.027. PubMed PMID: 20207474.

2: Gratzke C, Streng T, Stief CG, Alroy I, Limberg BJ, Downs TR, Rosenbaum JS, Hedlund P, Andersson KE. Cannabinor, a selective cannabinoid-2 receptor agonist, improves bladder emptying in rats with partial urethral obstruction. J Urol. 2011 Feb;185(2):731-6. doi: 10.1016/j.juro.2010.09.080. PubMed PMID: 21168864.