WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 529415
Description: Cannabinor, also known as PRS-211375 and PRS 375, is a cannabinoid CB2 agonist potentially for the treatment of partial urethral obstruction.
MedKoo Cat#: 529415
Chemical Formula: C28H38O6
Exact Mass: 470.2668
Molecular Weight: 470.6
Elemental Analysis: C, 71.46; H, 8.14; O, 20.40
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
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Synonym: PRS-211375; PRS211375; PRS 211375; PRS-375; PRS375; PRS 375; Cannabinor
IUPAC/Chemical Name: (E)-4-(2-((1S,2S,5S)-6,6-dimethyl-4-oxobicyclo[3.1.1]heptan-2-yl)-3-hydroxy-5-(2-methyloctan-2-yl)phenoxy)-4-oxobut-2-enoic acid
InChi Key: GSTZHANFXAKPSE-MXTREEOPSA-N
InChi Code: InChI=1S/C28H38O6/c1-6-7-8-9-12-27(2,3)17-13-22(30)26(23(14-17)34-25(33)11-10-24(31)32)18-15-21(29)20-16-19(18)28(20,4)5/h10-11,13-14,18-20,30H,6-9,12,15-16H2,1-5H3,(H,31,32)/b11-10+/t18-,19-,20+/m0/s1
SMILES Code: O=C(OC1=CC(C(C)(C)CCCCCC)=CC(O)=C1[C@@H](C2)[C@@](C3)([H])C(C)(C)[C@@]3([H])C2=O)/C=C/C(O)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 470.6 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Gratzke C, Streng T, Stief CG, Downs TR, Alroy I, Rosenbaum JS, Andersson KE, Hedlund P. Effects of cannabinor, a novel selective cannabinoid 2 receptor agonist, on bladder function in normal rats. Eur Urol. 2010 Jun;57(6):1093-100. doi: 10.1016/j.eururo.2010.02.027. PubMed PMID: 20207474.
2: Gratzke C, Streng T, Stief CG, Alroy I, Limberg BJ, Downs TR, Rosenbaum JS, Hedlund P, Andersson KE. Cannabinor, a selective cannabinoid-2 receptor agonist, improves bladder emptying in rats with partial urethral obstruction. J Urol. 2011 Feb;185(2):731-6. doi: 10.1016/j.juro.2010.09.080. PubMed PMID: 21168864.