WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 530500

CAS#: 1436383-95-7

Description: BF738735 is a potent and selective PI4KIIIβ Inhibitor. BF738735 displays antiviral property. BF738735 targets OSBP and inhibit cholesterol shuttling to replication organelles.

Price and Availability




BF738735 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 530500
Name: BF738735
CAS#: 1436383-95-7
Chemical Formula: C21H19FN4O3S
Exact Mass: 426.1162
Molecular Weight: 426.4664
Elemental Analysis: C, 59.14; H, 4.49; F, 4.45; N, 13.14; O, 11.25; S, 7.52

Synonym: BF738735; BF-738735; BF 738735.

IUPAC/Chemical Name: 2-fluoro-4-(2-methyl-8-((3-(methylsulfonyl)benzyl)amino)imidazo[1,2-a]pyrazin-3-yl)phenol


InChi Code: InChI=1S/C21H19FN4O3S/c1-13-19(15-6-7-18(27)17(22)11-15)26-9-8-23-20(21(26)25-13)24-12-14-4-3-5-16(10-14)30(2,28)29/h3-11,27H,12H2,1-2H3,(H,23,24)

SMILES Code: OC1=CC=C(C=C1F)C2=C(C)N=C3C(NCC4=CC=CC(S(=O)(C)=O)=C4)=NC=CN32

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:


1. van der Schaar, Hilde M.; Leyssen, Pieter; Thibaut, Hendrik J.; de Palma, Armando; van der Linden, Lonneke; Lanke, Kjerstin H. W.; Lacroix, Celine; Verbeken, Erik; Conrath, Katja; MacLeod, Angus M.; et al A novel, broad-​spectrum inhibitor of enterovirus replication that targets host cell factor phosphatidylinositol 4-​kinase IIIβ. Antimicrobial Agents and Chemotherapy (2013), 57(10), 4971-4981.

2. MacLeod, Angus M.; Mitchell, Dale R.; Palmer, Nicholas J.; Van de Poel, Herve; Conrath, Katja; Andrews, Martin; Leyssen, Pieter; Neyts, Johan Identification of a Series of Compounds with Potent Antiviral Activity for the Treatment of Enterovirus Infections. ACS Medicinal Chemistry Letters (2013), 4(7), 585-589.