WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 531656
CAS#: 862891-27-8
Description: CAY10583 is a synthetic leukotriene B4 receptor type 2 (BLT2) agonist. CAY10583 directly promotes keratinocyte migration and indirectly enhances fibroblast proliferation by increasing keratinocyte production of TGF-β1 and bFGF, accelerating wound closure. CAY10583 is a promising pharmaceutical agent for diabetic wounds.
MedKoo Cat#: 531656
Name: CAY10583
CAS#: 862891-27-8
Chemical Formula: C25H25NO3
Exact Mass: 387.1834
Molecular Weight: 387.48
Elemental Analysis: C, 77.49; H, 6.50; N, 3.61; O, 12.39
Synonym: CAY10583; CAY 10583; CAY-10583.
IUPAC/Chemical Name: 2-{4-[(N-phenylpentanamido)methyl]phenyl}benzoic acid
InChi Key: IUJTVDNJFPZYBL-UHFFFAOYSA-N
InChi Code: InChI=1S/C25H25NO3/c1-2-3-13-24(27)26(21-9-5-4-6-10-21)18-19-14-16-20(17-15-19)22-11-7-8-12-23(22)25(28)29/h4-12,14-17H,2-3,13,18H2,1H3,(H,28,29)
SMILES Code: O=C(O)C1=CC=CC=C1C2=CC=C(CN(C3=CC=CC=C3)C(CCCC)=O)C=C2
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 387.48 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Luo L, Tanaka R, Kanazawa S, Lu F, Hayashi A, Yokomizo T, Mizuno H. A synthetic leukotriene B(4) receptor type 2 agonist accelerates the cutaneous wound healing process in diabetic rats by indirect stimulation of fibroblasts and direct stimulation of keratinocytes. J Diabetes Complications. 2017 Jan;31(1):13-20. doi: 10.1016/j.jdiacomp.2016.09.002. PubMed PMID: 27742551.
