NGX-267
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MedKoo CAT#: 529509

CAS#: 503431-81-0 (free base)

Description: NGX-267 is a muscarinic M1 agonist potentially for the treatment of Xerostomia, Alzheimer's disease and cognitive


Price and Availability

Size Price Shipping out time Quantity
5mg USD 400 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2020-10-29. Prices are subject to change without notice.

NGX-267, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 529509
Name: NGX-267
CAS#: 503431-81-0 (free base)
Chemical Formula: C10H18N2OS
Exact Mass: 214.114
Molecular Weight: 214.32
Elemental Analysis: C, 56.04; H, 8.47; N, 13.07; O, 7.46; S, 14.96


Related CAS #: 503431-81-0 (free base)   869377-75-3 (hydrate)    

Synonym: NGX-267; AF-267B; NGX267; AF267B; NGX 267; AF 267B

IUPAC/Chemical Name: (S)-2-ethyl-8-methyl-1-thia-4,8-diazaspiro[4.5]decan-3-one

InChi Key: PHOZOHFUXHPOCK-QMMMGPOBSA-N

InChi Code: InChI=1S/C10H18N2OS/c1-3-8-9(13)11-10(14-8)4-6-12(2)7-5-10/h8H,3-7H2,1-2H3,(H,11,13)/t8-/m0/s1

SMILES Code: O=C1[C@H](CC)SC2(CCN(C)CC2)N1


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001


References

1: Heinrich JN, Butera JA, Carrick T, Kramer A, Kowal D, Lock T, Marquis KL,
Pausch MH, Popiolek M, Sun SC, Tseng E, Uveges AJ, Mayer SC. Pharmacological
comparison of muscarinic ligands: historical versus more recent muscarinic
M1-preferring receptor agonists. Eur J Pharmacol. 2009 Mar 1;605(1-3):53-6. doi:
10.1016/j.ejphar.2008.12.044. PubMed PMID: 19168056.