Veledimex

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 529812

CAS#: 1093130-72-3

Description: Veledimex, also known as AD-1001, INXN-1001 and RG-115932 is a drug potentially for the treatment of melanoma and breast cancer

Chemical Structure

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Veledimex
CAS# 1093130-72-3
Instruction

Theoretical Analysis

MedKoo Cat#: 529812
Name: Veledimex
CAS#: 1093130-72-3
Chemical Formula: C27H38N2O3
Exact Mass: 438.29
Molecular Weight: 438.612
Elemental Analysis: C, 73.94; H, 8.73; N, 6.39; O, 10.94

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Related CAS #: 1093130-72-3    

Synonym: AD-1001; AD1001; AD 1001; INXN-1001;INXN1001; INXN 1001; RG-115932; RG115932; RG 115932; Veledimex.

IUPAC/Chemical Name: (R)-N'-(3,5-dimethylbenzoyl)-N'-(2,2-dimethylhexan-3-yl)-2-ethyl-3-methoxybenzohydrazide

InChi Key: LZWZPGLVHLSWQX-XMMPIXPASA-N

InChi Code: InChI=1S/C27H38N2O3/c1-9-12-24(27(5,6)7)29(26(31)20-16-18(3)15-19(4)17-20)28-25(30)22-13-11-14-23(32-8)21(22)10-2/h11,13-17,24H,9-10,12H2,1-8H3,(H,28,30)/t24-/m1/s1

SMILES Code: O=C(NN(C(C1=CC(C)=CC(C)=C1)=O)[C@@H](C(C)(C)C)CCC)C2=CC=CC(OC)=C2CC

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 438.61 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Cai H, Sun L, Miao J, Krishman S, Lebel F, Barrett JA. Plasma Pharmacokinetics of Veledimex, a Small-Molecule Activator Ligand for a Proprietary Gene Therapy Promoter System, in Healthy Subjects. Clin Pharmacol Drug Dev. 2016 Jul 1. doi: 10.1002/cpdd.287. [Epub ahead of print] PubMed PMID: 27364771.