WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 530400

CAS#: 1370003-76-1

Description: YK-11 is a synthetic, steroidal selective androgen receptor modulator (SARM). It is a gene-selective partial agonist of the androgen receptor (AR) and does not induce the physical interaction between the NTD/AF1 and LBD/AF2 (known as the N/C interaction), which is required for full transactivation of the AR. The drug has anabolic activity in vitro in C2C12 myoblasts and shows greater potency than dihydrotestosterone (DHT) in this regard.

Chemical Structure

CAS# 1370003-76-1

Theoretical Analysis

MedKoo Cat#: 530400
Name: YK11
CAS#: 1370003-76-1
Chemical Formula: C25H34O6
Exact Mass: 430.2355
Molecular Weight: 430.541
Elemental Analysis: C, 69.74; H, 7.96; O, 22.30

Price and Availability

Size Price Availability Quantity
100.0mg USD 150.0 Same day
500.0mg USD 250.0 Same day
1.0g USD 450.0 Same day
2.0g USD 850.0 Same day
5.0g USD 1450.0 Same day
10.0g USD 2250.0 2 Weeks
50.0g USD 4950.0 2 Weeks
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Synonym: YK-11; YK 11; YK11.

IUPAC/Chemical Name: methyl (E)-2-((8R,9S,10R,13S,14S,17R)-2'-methoxy-2',13-dimethyl-3-oxo-1,2,3,6,7,8,9,10,11,12,13,14,15,16-tetradecahydrospiro[cyclopenta[a]phenanthrene-17,4'-[1,3]dioxolan]-5'-ylidene)acetate


InChi Code: InChI=1S/C25H34O6/c1-23-11-9-18-17-8-6-16(26)13-15(17)5-7-19(18)20(23)10-12-25(23)21(14-22(27)28-3)30-24(2,29-4)31-25/h13-14,17-20H,5-12H2,1-4H3/b21-14+/t17-,18+,19+,20-,23-,24?,25-/m0/s1

SMILES Code: C[C@@]12[C@](/C3=C\C(OC)=O)(OC(OC)(O3)C)CC[C@@]1([H])[C@]4([H])CCC5=CC(CC[C@]5([H])[C@@]4([H])CC2)=O

Appearance: White to off-white solid powder.

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 430.541 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Kanno Y, Ota R, Someya K, Kusakabe T, Kato K, Inouye Y. Selective androgen
receptor modulator, YK11, regulates myogenic differentiation of C2C12 myoblasts
by follistatin expression. Biol Pharm Bull. 2013;36(9):1460-5. PubMed PMID:

2: Kanno Y, Hikosaka R, Zhang SY, Inoue Y, Nakahama T, Kato K, Yamaguchi A,
Tominaga N, Kohra S, Arizono K, Inouye Y.
carboxylic acid methyl ester (YK11) is a partial agonist of the androgen
receptor. Biol Pharm Bull. 2011;34(3):318-23. PubMed PMID: 21372378.


100.0mg / USD 150.0