WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 530395

CAS#: 328998-25-0

Description: 4E1RCat is an inhibitor of the eIF4F translation initiation complex that blocks eIF4E:eIF4G and eIF4E:4E-BP1 interactions.

Price and Availability

Size Price Shipping out time Quantity
25mg USD 150 Same Day
50mg USD 250 Same Day
100mg USD 450 Same Day
200mg USD 750 Same Day
500mg USD 1550 Same Day
1g USD 2650 2 Weeks
2g USD 4250 2 Weeks
5g USD 6850 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2021-01-24. Prices are subject to change without notice.

4E1RCat, purity > 98%, is in stock.The same day shipping out after order is received.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 530395
Name: 4E1RCat
CAS#: 328998-25-0
Chemical Formula: C28H18N2O6
Exact Mass: 478.1165
Molecular Weight: 478.46
Elemental Analysis: C, 70.29; H, 3.79; N, 5.86; O, 20.06

Synonym: 4E1RCat; eIF4E/eIF4G Interaction Inhibitor II.

IUPAC/Chemical Name: (Z)-4-(3-((5-(4-nitrophenyl)furan-2-yl)methylene)-2-oxo-5-phenyl-2,3-dihydro-1H-pyrrol-1-yl)benzoic acid


InChi Code: InChI=1S/C28H18N2O6/c31-27-21(16-24-14-15-26(36-24)19-6-12-23(13-7-19)30(34)35)17-25(18-4-2-1-3-5-18)29(27)22-10-8-20(9-11-22)28(32)33/h1-17H,(H,32,33)/b21-16-

SMILES Code: O=C1/C(C=C(C2=CC=CC=C2)N1C3=CC=C(C(O)=O)C=C3)=C\C4=CC=C(C5=CC=C([N+]([O-])=O)C=C5)O4

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Certificate of Analysis:

Safety Data Sheet (SDS):

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Shuda M, Velásquez C, Cheng E, Cordek DG, Kwun HJ, Chang Y, Moore PS. CDK1
substitutes for mTOR kinase to activate mitotic cap-dependent protein
translation. Proc Natl Acad Sci U S A. 2015 May 12;112(19):5875-82. doi:
10.1073/pnas.1505787112. PubMed PMID: 25883264; PubMed Central PMCID: PMC4434708.

2: Arnold N, Koppula PR, Gul R, Luck C, Pulakat L. Regulation of cardiac
expression of the diabetic marker microRNA miR-29. PLoS One. 2014 Jul
25;9(7):e103284. doi: 10.1371/journal.pone.0103284. PubMed PMID: 25062042; PubMed
Central PMCID: PMC4111545.