UK 58852

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MedKoo CAT#: 526527

CAS#: 101621-29-8

Description: UK 58852 is a polyether ionophore.


Price and Availability

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Pricing updated 2020-10-29. Prices are subject to change without notice.

UK 58852 is not in stock, but may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 526527
Name: UK 58852
CAS#: 101621-29-8
Chemical Formula: C52H88O18
Exact Mass: 1000.5971
Molecular Weight: 1001.258
Elemental Analysis: C, 62.38; H, 8.86; O, 28.76


Synonym: UK 58852, UK58852, UK58852

IUPAC/Chemical Name: 2H-Pyran-2-acetic acid, tetrahydro-2-hydroxy-6-(1-(9-hydroxy-2,8-dimethyl-2-(octahydro-2-methyl-5'-(tetrahydro-6-hydroxy-3,5,6-trimethyl-2H-pyran-2-yl)-3'-((tetrahydro-5-methoxy-6-methyl-2H-pyran-2-yl)oxy)(2,2'-bifuran)-5-yl)-1,6-dioxaspiro(4,5)dec-7-yl)ethyl)-5-methoxy-3-methyl-4-((tetrahydro-5-methoxy-6-methyl-2H-pyran-2-yl)oxy)-, (2R-(2alpha,3alpha,4beta(2S*,5S*,6R*),5alpha,6beta(R*(2S*(2S*,2'R*,3'S*(2S*,5S*,6R*),5R*,5'R*(2S*,3S*,5R*,6S*)),5R*,7S*,8R*,9S*))))-

InChi Key: FERWJHOISPGQCT-NCWSHVJWSA-N

InChi Code: InChI=1S/C52H88O18/c1-26-22-27(2)50(10,56)67-42(26)36-23-37(63-40-16-14-34(58-11)31(6)61-40)47(64-36)49(9)19-18-38(66-49)48(8)20-21-51(70-48)24-33(53)28(3)43(68-51)29(4)44-46(60-13)45(30(5)52(57,69-44)25-39(54)55)65-41-17-15-35(59-12)32(7)62-41/h26-38,40-47,53,56-57H,14-25H2,1-13H3,(H,54,55)/t26?,27?,28-,29+,30-,31?,32?,33+,34?,35-,36?,37+,38?,40?,41-,42?,43+,44-,45-,46-,47?,48?,49?,50?,51?,52+/m1/s1

SMILES Code: O=C(O)C[C@@]1(O)[C@H](C)[C@@H](O[C@@H]2CC[C@@H](OC)C(C)O2)[C@H](OC)[C@@H]([C@H]([C@H]([C@H](C)[C@@H](O)C3)OC43CCC(C5CCC(C6OC(C7C(C)CC(C)C(C)(O)O7)C[C@@H]6OC8CCC(OC)C(C)O8)(C)O5)(C)O4)C)O1


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001


References

1: Ricketts AP, Chappel LR, Frame GM, Glazer EA, Migaki TT, Olson JA. CP-72,588, a semisynthetic analog of the polyether ionophore UK-58,582 with increased anticoccidial potency. Antimicrob Agents Chemother. 1992 Oct;36(10):2080-4. PubMed PMID: 1444288; PubMed Central PMCID: PMC245459.

2: Dirlam JP, Cullen WP, Huang LH, Nelson TH, Oscarson JR, Presseau-Linabury L, Tynan EJ, Whipple EB. CP-91,243 and CP-91,244, novel diglycoside polyether antibiotics related to UK-58,852 and produced by mutants of Actinomadura roseorufa. J Antibiot (Tokyo). 1991 Nov;44(11):1262-6. PubMed PMID: 1842675.