Mitapivat
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 329505

CAS#: 1260075-17-9 (free)

Description: Mitapivat, also known as PKM2 activator 1020 is a PKM2 activator (pyruvate kinase activator) for the treatment of pyruvate kinase deficiency.


Price and Availability

Size Price Shipping out time Quantity
100mg USD 950 2 Weeks
200mg USD 1450 2 Weeks
500mg USD 2250 2 Weeks
1g USD 3450 2 Weeks
2g USD 4850 2 Weeks
5g USD 8450 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2020-10-27. Prices are subject to change without notice.

Mitapivat, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 329505
Name: Mitapivat
CAS#: 1260075-17-9 (free)
Chemical Formula: C24H26N4O3S
Exact Mass: 450.1726
Molecular Weight: 450.557
Elemental Analysis: C, 63.98; H, 5.82; N, 12.44; O, 10.65; S, 7.12


Related CAS #: 2151847-10-6 (sulfate hydrate)   1260075-17-9 (free)   2329710-91-8 (sulfate)    

Synonym: AG348; AG-348; AG 348; PKR-IN-1; PKM2 activator 1020; PKM2 activator; Mitapivat.

IUPAC/Chemical Name: N-{4-[4-(cyclopropylmethyl)piperazine-1-carbonyl]phenyl}quinoline-8-sulfonamide

InChi Key: XAYGBKHKBBXDAK-UHFFFAOYSA-N

InChi Code: InChI=1S/C24H26N4O3S/c29-24(28-15-13-27(14-16-28)17-18-6-7-18)20-8-10-21(11-9-20)26-32(30,31)22-5-1-3-19-4-2-12-25-23(19)22/h1-5,8-12,18,26H,6-7,13-17H2

SMILES Code: O=S(C1=C2N=CC=CC2=CC=C1)(NC3=CC=C(C(N4CCN(CC5CC5)CC4)=O)C=C3)=O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001