WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 329495
Description: Delpazolid, also known as LCB01-0371, is a new oxazolidinone with cyclic amidrazone. In vitro activity of LCB01-0371 against 624 clinical isolates was evaluated and compared with those of linezolid, vancomycin, and other antibiotics. LCB01-0371 showed good activity against Gram-positive pathogens. In vivo activity of LCB01-0371 against systemic infections in mice was also evaluated. LCB01-0371 was more active than linezolid against these systemic infections. LCB01-0371 showed bacteriostatic activity against Staphylococcus aureus.
MedKoo Cat#: 329495
Chemical Formula: C14H17FN4O3
Exact Mass: 308.1285
Molecular Weight: 308.3134
Elemental Analysis: C, 54.54; H, 5.56; F, 6.16; N, 18.17; O, 15.57
Synonym: Delpazolid; LCB01-0371; LCB 01-0371; LCB-01-0371; LCB010371; LCB 010371; LCB-010371.
IUPAC/Chemical Name: (5R)-3-[3-fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4(1H)-yl)phenyl]-5-(hydroxymethyl)-1,3-oxazolidin-2-one
InChi Key: QLUWQAFDTNAYPN-LLVKDONJSA-N
InChi Code: InChI=1S/C14H17FN4O3/c1-17-4-5-18(9-16-17)13-3-2-10(6-12(13)15)19-7-11(8-20)22-14(19)21/h2-3,6,9,11,20H,4-5,7-8H2,1H3/t11-/m1/s1
SMILES Code: O=C1O[C@@H](CO)CN1C2=CC=C(N3C=NN(C)CC3)C(F)=C2