WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 329489

CAS#: 1228088-30-9

Description: Balovaptan, also known as RG7314, is a vasopressin receptor antagonist. Balovaptan has shown potential as a treatment for people with autism spectrum disorder (ASD). Balovaptan has shown the potential to improve social interaction and communication in people with ASD. Balovaptan is an investigational small molecule currently in clinical development by Roche for the treatment of ASD. It acts as a vasopressin (V1a) receptor antagonist.

Price and Availability




Balovaptan is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 329489
Name: Balovaptan
CAS#: 1228088-30-9
Chemical Formula: C22H24ClN5O
Exact Mass: 409.1669
Molecular Weight: 409.918
Elemental Analysis: C, 64.46; H, 5.90; Cl, 8.65; N, 17.09; O, 3.90

Synonym: RG7314; RG 7314; RG-7314; Balovaptan

IUPAC/Chemical Name: 8-chloro-5-methyl-1-{trans-4-[(pyridin-2-yl)oxy]cyclohexyl}-5,6-dihydro-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine


InChi Code: InChI=1S/C22H24ClN5O/c1-27-13-16-12-17(23)7-10-19(16)28-20(14-27)25-26-22(28)15-5-8-18(9-6-15)29-21-4-2-3-11-24-21/h2-4,7,10-12,15,18H,5-6,8-9,13-14H2,1H3/t15-,18-

SMILES Code: CN1CC2=NN=C([C@H]3CC[C@H](OC4=NC=CC=C4)CC3)[N@]2[C@]5=CC=C(Cl)C=C5C1

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:

Additional Information

The World Health Organisation estimates that global prevalence of ASD is around one in every 160 people; in the EU, prevalence estimates range from 57 to 67 per 10,000 children. Evidence from both human and animal studies implicate the V1a receptor in mediating and modulating key social behaviours that are challenging for individuals with ASD.