NSC23005 sodium
featured

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 530373

CAS#: 1796596-46-7 (sodium)

Description: NSC23005 is a p18INK inhibitor. NSC23005 potently promotes hematopoietic stem cell (HSC) expansion (ED50 = 5.21 nM).

Chemical Structure

img
NSC23005 sodium
CAS# 1796596-46-7 (sodium)
Product data Instruction

Theoretical Analysis

MedKoo Cat#: 530373
Name: NSC23005 sodium
CAS#: 1796596-46-7 (sodium)
Chemical Formula: C13H16NNaO4S
Exact Mass: 0.00
Molecular Weight: 305.324
Elemental Analysis: C, 51.14; H, 5.28; N, 4.59; Na, 7.53; O, 20.96; S, 10.50

Price and Availability

Size Price Availability Quantity
200mg USD 650 2 Weeks
500mg USD 1450 2 Weeks
1g USD 2450 2 Weeks
2g USD 4250 2 Weeks
Bulk inquiry

Related CAS #: 1796596-46-7 (sodium)   6314-70-1 (free acid)    

Synonym: p18SMI-40; NSC23005 sodium; NSC23005; NSC-23005; NSC 23005.

IUPAC/Chemical Name: Sodium 4-(N-cyclohexylsulfamoyl)benzoate

InChi Key: MLHFBDVMTRIQMW-UHFFFAOYSA-M

InChi Code: InChI=1S/C13H17NO4S.Na/c15-13(16)10-6-8-12(9-7-10)19(17,18)14-11-4-2-1-3-5-11;/h6-9,11,14H,1-5H2,(H,15,16);/q;+1/p-1

SMILES Code: O=C([O-])C1=CC=C(S(=O)(NC2CCCCC2)=O)C=C1.[Na+]

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info: Related CAS# CAS#1796596-46-7 (NSC23005 sodium) CAS#6314-70-1 (NSC23005)

Product Data:
Product Data
Instruction:
View handling instruction
Biological target: NSC23005 sodium is a novel and effective p18 inhibitor (ED50=5.21 nM).
In vitro activity: TBD
In vivo activity: TBD

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMF 0.2 0.66
DMSO 22.8 74.67
Ethanol 3.6 11.79
PBS (pH 7.2) 10.0 32.75
Water 80.5 263.65

Preparing Stock Solutions

The following data is based on the product molecular weight 305.32 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol: TBD
In vitro protocol: TBD
In vivo protocol: TBD

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

Xie et al (2015) Discovery of novel INK4C small-molecule inhibitors to promote human and murine hematopoietic stem cell ex vivo expansion. Sci.Rep. 5 18115 PMID: 26681454