SU 5201
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 530466

CAS#: 114727-43-4

Description: SU 5201 is an inhibitor of IL-2 production. It inhibits IL-2 production in peripheral blood mononuclear cells (PBMCs) with an IC50 value of 1 nM. SU 5201 also inhibits VEGF- or acidic FGF-induced proliferation of human umbilical vein endothelial cells (HUVECs) when used at concentrations of 2.5 and 2.3 µM, respectively.

Chemical Structure

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SU 5201
CAS# 114727-43-4
Product data Instruction

Theoretical Analysis

MedKoo Cat#: 530466
Name: SU 5201
CAS#: 114727-43-4
Chemical Formula: C15H9Cl2NO
Exact Mass: 289.01
Molecular Weight: 290.143
Elemental Analysis: C, 62.10; H, 3.13; Cl, 24.44; N, 4.83; O, 5.51

Price and Availability

Size Price Availability Quantity
1g USD 2850
2g USD 3950
5g USD 5750
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Synonym: NSC 247030; NSC-247030; NSC247030; SU 5201; SU5201; SU-5201;

IUPAC/Chemical Name: (3,4-Dichlorobenzylidene)-1,3-dihydroindol-2-one

InChi Key: RCJZXLNWNCVIMJ-XFFZJAGNSA-N

InChi Code: InChI=1S/C15H9Cl2NO/c16-12-6-5-9(8-13(12)17)7-11-10-3-1-2-4-14(10)18-15(11)19/h1-8H,(H,18,19)/b11-7-

SMILES Code: O=C1NC2=C(C=CC=C2)/C1=C/C3=CC=C(Cl)C(Cl)=C3

Appearance: Yellow solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Product Data:
Product Data
Instruction:
View handling instruction
Biological target: SU5201 is an inhibitor of interleukin-2 (IL-2) production.
In vitro activity: TBD
In vivo activity: TBD

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMF 30.0 103.40
DMF:PBS (pH 7.2) (1:2) 0.3 1.03
DMSO 20.0 68.93

Preparing Stock Solutions

The following data is based on the product molecular weight 290.14 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol: TBD
In vitro protocol: TBD
In vivo protocol: TBD

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